OMIA 001614-9685 : Vitamin D-deficiency rickets, non-type I, non-type II in Felis catus
Mendelian trait/disorder: unknown Considered a defect: yes Species-specific description: This disorder is characterised by low levels of both 25-hydroxy-vitamin-D [25(HO)D] and 1,25-hydroxy-vitamin-D [1,25(HO)D], which thus distinguishes it from type I (normal 25(HO)D, low 1,25(HO)D) and type II (normal 25(HO)D, high 1,25(HO)D). History: Phillips et al. (2011) described this condition in one kitten in a litter of four fed an identical ration. On the basis of this and other evidence, they suggested that this disorder could be due to an inborn error of metabolism, i.e. an enzyme deficiency due to a mutation in the corresponding gene. Breed: Cornish Rex.
|2011||Phillips, A.M., Fawcett, A.C., Allan, G.S., Wilkinson, M., Fraser, D.R., Malik, R. :|
|Vitamin D-dependent non-type 1, non-type 2 rickets in a 3-month-old Cornish Rex kitten. J Feline Med Surg 13:526-31, 2011. Pubmed reference: 21704902. DOI: 10.1016/j.jfms.2011.05.010.|
- Created by Frank Nicholas on 30 Sep 2011