OMIA:001764-30538 : Choanal atresia in Vicugna pacos (alpaca)

In other species: dog , domestic cat , ass (donkey) , horse , llama , sheep

Categories: Respiratory system phene

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 608911 (trait) , 214800 (trait)

Links to MONDO diseases: No links.

Mendelian trait/disorder: unknown

Considered a defect: yes

Molecular basis: Investigation of a comparative candidate gene (CHD7) led to Reed et al. (2013) concluding that mutations in this gene "do not appear to be the primary cause of CA in alpacas".

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2013). OMIA:001764-30538: Online Mendelian Inheritance in Animals (OMIA) [dataset].


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2024 Neubert, S., Puff, C., Kleinschmidt, S., Kammeyer, P., von Altrock, A., Wendt, M., Wagener, M.G. :
Pathological findings in South American camelids presented at a farm animal clinic in Northern Germany (2005-2021). Vet Res Commun , 2024. Pubmed reference: 38630427. DOI: 10.1007/s11259-024-10369-1.
2020 Jost, S.M., Knoll, A., Lühken, G., Drögemüller, C., Zanolari, P. :
Prevalence of coat colour traits and congenital disorders of South American camelids in Austria, Germany and Switzerland. Acta Vet Scand 62:56, 2020. Pubmed reference: 32948208. DOI: 10.1186/s13028-020-00554-y.
2013 Reed, K.M., Mendoza, K.M., Fleege, E.C., Damerow, J.A., Armién, A.G. :
Evaluation of CHD7 as a candidate gene for choanal atresia in alpacas (Vicugna pacos). Vet J , 2013. Pubmed reference: 23932654. DOI: 10.1016/j.tvjl.2013.07.006.
2010 Reed, K.M., Bauer, M.M., Mendoza, K.M., Armién, A.G. :
A candidate gene for choanal atresia in alpaca. Genome 53:224-30, 2010. Pubmed reference: 20237599. DOI: 10.1139/g09-100.

Edit History

  • Created by Frank Nicholas on 16 Aug 2013
  • Changed by Frank Nicholas on 16 Aug 2013