OMIA 001771-7091 : "Ming" lethal egg in Bombyx mori

Mendelian trait/disorder: yes

Mode of inheritance: Autosomal Recessive

Considered a defect: yes

Key variant known: yes

Year key variant first reported: 2013

Associated gene:

Symbol Description Species Chr Location OMIA gene details page Other Links
NEWENTRY Record to support submission of GeneRIFs for a gene not in Gene (domestic silkworm; silk moth; silkworm). Bombyx mori - no genomic information (-..-) NEWENTRY Homologene, Ensembl, NCBI gene

Variants

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WARNING! Inclusion of a variant in this table does not automatically mean that it should be used for DNA testing. Anyone contemplating the use of any of these variants for DNA testing should examine critically the relevant evidence (especially in breeds other than the breed in which the variant was first described). If it is decided to proceed, the location and orientation of the variant sequence should be checked very carefully.

Breed(s) Variant Phenotype Gene Allele Type of Variant Reference Sequence Chr. g. or m. c. or n. p. Verbal Description EVA ID Year Published PubMed ID(s) Acknowledgements
"Ming" lethal egg NEWENTRY complex rearrangement an ~1.9 kb region from the 3' untranslated region of BmVMP23 to the forepart of BmEP80 was replaced by a >100 kb DNA fragment 2013 23262333

Reference


2013 Chen, A., Gao, P., Zhao, Q., Tang, S., Shen, X., Zhang, G., Qiu, Z., Xia, D., Huang, Y., Xu, Y., He, N. :
Mutation of a vitelline membrane protein, BmEP80, is responsible for the silkworm "Ming" lethal egg mutant. Gene 515:313-9, 2013. Pubmed reference: 23262333. DOI: 10.1016/j.gene.2012.12.006.

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  • Created by Frank Nicholas on 06 Feb 2013