OMIA 001787-9615 : Squamous cell carcinoma of the digit in Canis lupus familiaris |
Symbol | Description | Species | Chr | Location | OMIA gene details page | Other Links |
---|---|---|---|---|---|---|
KITLG | KIT ligand | Canis lupus familiaris | 15 | NC_051819.1 (30311189..30230533) | KITLG | Homologene, Ensembl, NCBI gene |
Variants
By default, variants are sorted chronologically by year of publication, to provide a historical perspective. Readers can re-sort on any column by clicking on the column header. Click it again to sort in a descending order. To create a multiple-field sort, hold down Shift while clicking on the second, third etc relevant column headers.
WARNING! Inclusion of a variant in this table does not automatically mean that it should be used for DNA testing. Anyone contemplating the use of any of these variants for DNA testing should examine critically the relevant evidence (especially in breeds other than the breed in which the variant was first described). If it is decided to proceed, the location and orientation of the variant sequence should be checked very carefully.
Since October 2021, OMIA includes a semiautomated lift-over pipeline to facilitate updates of genomic positions to a recent reference genome position. These changes to genomic positions are not always reflected in the ‘acknowledgements’ or ‘verbal description’ fields in this table.
OMIA Variant ID | Breed(s) | Variant Phenotype | Gene | Allele | Type of Variant | Source of Genetic Variant | Reference Sequence | Chr. | g. or m. | c. or n. | p. | Verbal Description | EVA ID | Inferred EVA rsID | Year Published | PubMed ID(s) | Acknowledgements |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
757 | Standard Poodle | Squamous cell carcinoma of the digit | KITLG | repeat variation | Naturally occurring variant | 15 | a copy number variant (CNV) of KITLG | 2013 | 23555311 |
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2016 | Marsden, C.D., Ortega-Del Vecchyo, D., O'Brien, D.P., Taylor, J.F., Ramirez, O., Vilà, C., Marques-Bonet, T., Schnabel, R.D., Wayne, R.K., Lohmueller, K.E. : | |
Bottlenecks and selective sweeps during domestication have increased deleterious genetic variation in dogs. Proc Natl Acad Sci U S A 113:152-7, 2016. Pubmed reference: 26699508. DOI: 10.1073/pnas.1512501113. | ||
2014 | Davis, B.W., Ostrander, E.A. : | |
Domestic dogs and cancer research: a breed-based genomics approach. ILAR J 55:59-68, 2014. Pubmed reference: 24936030. DOI: 10.1093/ilar/ilu017. | ||
2013 | Karyadi, D.M., Karlins, E., Decker, B., Vonholdt, B.M., Carpintero-Ramirez, G., Parker, H.G., Wayne, R.K., Ostrander, E.A. : | |
A Copy Number Variant at the KITLG Locus Likely Confers Risk for Canine Squamous Cell Carcinoma of the Digit. PLoS Genet 9:e1003409, 2013. Pubmed reference: 23555311. DOI: 10.1371/journal.pgen.1003409. | ||
2008 | Goldschmidt, M., Hendrick, M. : | |
Tumors of the Skin and Soft Tissues. In: Tumors in Domestic Animals. Meuten DJ, editor. Ames, Iowa: Iowa State University Press :45–119, 2008. | ||
2007 | Wobeser, B.K., Kidney, B.A., Powers, B.E., Withrow, S.J., Mayer, M.N., Spinato, M.T., Allen, A.L. : | |
Agreement among surgical pathologists evaluating routine histologic sections of digits amputated from cats and dogs. J Vet Diagn Invest 19:439-43, 2007. Pubmed reference: 17609360. | ||
2005 | Henry, C.J., Brewer, W.G., Whitley, E.M., Tyler, J.W., Ogilvie, G.K., Norris, A., Fox, L.E., Morrison, W.B., Hammer, A., Vail, D.M., Berg, J. : | |
Canine digital tumors: a veterinary cooperative oncology group retrospective study of 64 dogs. J Vet Intern Med 19:720-4, 2005. Pubmed reference: 16231717. | ||
1995 | Marino, D.J., Matthiesen, D.T., Stefanacci, J.D., Moroff, S.D. : | |
Evaluation of dogs with digit masses: 117 cases (1981-1991). J Am Vet Med Assoc 207:726-8, 1995. Pubmed reference: 7657570. | ||
1992 | O'Brien, M.G., Berg, J., Engler, S.J. : | |
Treatment by digital amputation of subungual squamous cell carcinoma in dogs: 21 cases (1987-1988) J Am Vet Med Assoc 201:759-61, 1992. Pubmed reference: 1399782. | ||
1989 | Paradis, M., Scott, D.W., Breton, L. : | |
Squamous cell carcinoma of the nail bed in three related giant schnauzers. Vet Rec 125:322-4, 1989. Pubmed reference: 2800263. | ||
1984 | Goldschmidt, M.H. : | |
Basal- and squamous-cell neoplasms of dogs and cats. Am J Dermatopathol 6:199-206, 1984. Pubmed reference: 6731733. | ||
1983 | Frese, K., Frank, H., Eskens, U. : | |
[Squamous cell carcinoma of the toes in dogs]. Dtsch Tierarztl Wochenschr 90:359-63, 1983. Pubmed reference: 6354679. |
Edit History
- Created by Frank Nicholas on 23 Apr 2013
- Changed by Frank Nicholas on 23 Apr 2013