OMIA 001952-9940 : Microtia in Ovis aries
Mastrangelo et al. (2018) obtained a strong signal on a different chromosome: "A total of 40 individuals, 20 with microtia and 20 normal, were genotyped with the Illumina OvineSNP50 BeadChip. The comparison among the results from a genome-wide association study, Fisher's exact test and FST analysis revealed a single strong association signal: rs419889303 on chromosome 1, located within intron 3 of the CLRN1 gene. Our study suggests for the first time that this novel candidate gene is responsible for microtia in sheep."Breed: Awassi.
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
|2018||Mastrangelo, S., Sottile, G., Sutera, A.M., Di Gerlando, R., Tolone, M., Moscarelli, A., Sardina, M.T., Portolano, B., Mastrangelo, S., Sottile, G., Sutera, A.M., Di Gerlando, R., Tolone, M., Moscarelli, A., Sardina, M.T., Portolano, B. :|
|Genome-wide association study reveals the locus responsible for microtia in Valle del Belice sheep breed. Anim Genet 49:636-640, 2018. Pubmed reference: 30160299. DOI: 10.1111/age.12719.|
|2016||Jawasreh, K., Boettcher, P.J., Stella, A. :|
|Genome-wide association scan suggests basis for microtia in Awassi sheep. Anim Genet 47:504-6, 2016. Pubmed reference: 26990958. DOI: 10.1111/age.12431.|
|2002||Porter, V. :|
|Mason's World Dictionary of Livestock Breeds, Types and Varieties. 5th edn. C.A.B International, Wallingford, UK. :, 2002.|
|1930||Lush, J.L. :|
|Earlessness in Karakul sheep Journal of Heredity 21:107-112, 1930.|
- Created by Frank Nicholas on 26 Mar 2016
- Changed by Frank Nicholas on 03 Sep 2018