OMIA 001961-9940 : Fecundity, Vacaria, FecG(V) in Ovis aries
|Symbol||Description||Species||Chr||Location||OMIA gene details page||Other Links|
|GDF9||growth differentiation factor 9||Ovis aries||5||NC_040256.1 (46547527..46544800)||GDF9||Homologene, Ensembl, NCBI gene|
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WARNING! Inclusion of a variant in this table does not automatically mean that it should be used for DNA testing. Anyone contemplating the use of any of these variants for DNA testing should examine critically the relevant evidence (especially in breeds other than the breed in which the variant was first described). If it is decided to proceed, the location and orientation of the variant sequence should be checked very carefully.
|Breed(s)||Variant Phenotype||Gene||Allele||Type of Variant||Reference Sequence||Chr.||g. or m.||c. or n.||p.||Verbal Description||EVA ID||Year Published||PubMed ID(s)||Acknowledgements|
|Ile de France||Fecundity, Vacaria, FecG(V)||GDF9||missense||Oar_v3.1||5||g.41841453C>T||c.943C>T||p.R315C||2014||25039891||Variant coordinates obtained from or confirmed by EBI's Some Effect Predictor (VEP) tool|
|2014||Souza, C.J., McNeilly, A.S., Benavides, M.V., Melo, E.O., Moraes, J.C. :|
|Mutation in the protease cleavage site of GDF9 increases ovulation rate and litter size in heterozygous ewes and causes infertility in homozygous ewes. Anim Genet 45:732-9, 2014. Pubmed reference: 25039891. DOI: 10.1111/age.12190.|
- Created by Frank Nicholas on 30 Apr 2015