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OMIA:001972-9798 : Coat colour, dun in Equus przewalskii (Przewalski's horse)

In other species: ass (donkey) , horse

Categories: Pigmentation phene

Links to possible relevant human trait(s) and/or gene(s) in OMIM: 601621 (gene)

Mendelian trait/disorder: yes

Considered a defect: no

Key variant known: yes

Molecular basis: Musiał et al. (2023) investigated the presence of two equine TBX3 variants (see OMIA:001972-9796 : Coat colour, dun in Equus caballus) and a MC1R variant associated with 'fox' colour in 23 Przewalski horses: "The coat color genes analyses indicated only native, wild genotypes. ... The results assigned all horses to the [TBX3] genotype with G/G alleles in both SNP loci, and deletions were not observed. ... none of Przewalski horses presented C to T missense mutation associated with an unfavorable [MC1R] ‘fox’ color variant for this species."

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2023). OMIA:001972-9798: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70

References

Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2023 Musiał, A.D., Ropka-Molik, K., Stefaniuk-Szmukier, M., Myćka, G., Bieniek, A., Yasynetska, N. :
Characteristic of Przewalski horses population from Askania-Nova reserve based on genetic markers. Mol Biol Rep 50:7121-7126, 2023. Pubmed reference: 37365410. DOI: 10.1007/s11033-023-08581-4.
2016 Imsland, F., McGowan, K., Rubin, C.J., Henegar, C., Sundström, E., Berglund, J., Schwochow, D., Gustafson, U., Imsland, P., Lindblad-Toh, K., Lindgren, G., Mikko, S., Millon, L., Wade, C., Schubert, M., Orlando, L., Penedo, M.C., Barsh, G.S., Andersson, L. :
Regulatory mutations in TBX3 disrupt asymmetric hair pigmentation that underlies Dun camouflage color in horses. Nat Genet 48:152-8, 2016. Pubmed reference: 26691985. DOI: 10.1038/ng.3475.

Edit History


  • Created by Imke Tammen2 on 28 Jun 2023
  • Changed by Imke Tammen2 on 28 Jun 2023