OMIA:001972-9798 : Coat colour, dun in Equus przewalskii (Przewalski's horse)
Categories: Pigmentation phene
Possibly relevant human trait(s) and/or gene(s) (MIM number): 601621 (gene)
Links to MONDO diseases: No links.
Mendelian trait/disorder: yes
Considered a defect: no
Key variant known: yes
Molecular basis: Musiał et al. (2023) investigated the presence of two equine TBX3 variants (see OMIA:001972-9796 : Coat colour, dun in Equus caballus) and a MC1R variant associated with 'fox' colour in 23 Przewalski horses: "The coat color genes analyses indicated only native, wild genotypes. ... The results assigned all horses to the [TBX3] genotype with G/G alleles in both SNP loci, and deletions were not observed. ... none of Przewalski horses presented C to T missense mutation associated with an unfavorable [MC1R] ‘fox’ color variant for this species."
Have human generated variants been created, e.g. through genetic engineering and gene editing
Cite this entry
|2023||Musiał, A.D., Ropka-Molik, K., Stefaniuk-Szmukier, M., Myćka, G., Bieniek, A., Yasynetska, N. :|
|Characteristic of Przewalski horses population from Askania-Nova reserve based on genetic markers. Mol Biol Rep , 2023. Pubmed reference: 37365410. DOI: 10.1007/s11033-023-08581-4.|
- Created by Imke Tammen2 on 28 Jun 2023
- Changed by Imke Tammen2 on 28 Jun 2023