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OMIA:002011-9823 : B-cell deficiency in Sus scrofa (pig)

Categories: Immune system phene

Mendelian trait/disorder: yes

Disease-related: yes

Key variant known: no

Species-specific description: This phene includes references to studies involving gene edited or genetically modified organisms (GMO).

Genetic engineering: Yes - variants have been created artificially, e.g. by genetic engineering or gene editing
Have human generated variants been created, e.g. through genetic engineering and gene editing

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2023). OMIA:002011-9823: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70

Reference

2015 Chen, F., Wang, Y., Yuan, Y., Zhang, W., Ren, Z., Jin, Y., Liu, X., Xiong, Q., Chen, Q., Zhang, M., Li, X., Zhao, L., Li, Z., Wu, Z., Zhang, Y., Hu, F., Huang, J., Li, R., Dai, Y. :
Generation of B cell-deficient pigs by highly efficient CRISPR/Cas9-mediated gene targeting. J Genet Genomics 42:437-44, 2015. Pubmed reference: 26336800. DOI: 10.1016/j.jgg.2015.05.002.

Edit History


  • Created by Frank Nicholas on 05 May 2016
  • Changed by Imke Tammen2 on 28 Oct 2022
  • Changed by Imke Tammen2 on 18 Dec 2023