OMIA 002046-9615 : Glaucoma, primary open angle in Canis lupus familiaris

Mendelian trait/disorder: unknown

Considered a defect: yes

Markers: Kanemaki et al. (2013) reported associations between SRBD1 polymorphisms and open-angle glaucoma in Shiba-Inus and Shih-Tzus, but likely causal variants remain to be discovered.


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2019 Park, S.A., Sledge, D., Monahan, C., Bartoe, J.T., Komáromy, A.M. :
Primary angle-closure glaucoma with goniodysgenesis in a Beagle dog. BMC Vet Res 15:75, 2019. Pubmed reference: 30832652. DOI: 10.1186/s12917-019-1812-1.
2017 Graham, K.L., McCowan, C., White, A. :
Genetic and biochemical biomarkers in canine glaucoma. Vet Pathol 54:194-203, 2017. Pubmed reference: 27681326. DOI: 10.1177/0300985816666611.
2013 Kanemaki, N., Tchedre, K.T., Imayasu, M., Kawarai, S., Sakaguchi, M., Yoshino, A., Itoh, N., Meguro, A., Mizuki, N. :
Dogs and Humans Share a Common Susceptibility Gene SRBD1 for Glaucoma Risk. PLoS One 8:e74372, 2013. Pubmed reference: 24040232. DOI: 10.1371/journal.pone.0074372.

Edit History

  • Created by Frank Nicholas on 07 Oct 2016
  • Changed by Frank Nicholas on 07 Oct 2016