OMIA:002060-9541 : Adrenal hypoplasia, congenital in Macaca fascicularis |
Categories: Endocrine / exocrine gland phene (incl mammary gland)
Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 300200 (trait) , 300473 (gene)
Links to MONDO diseases:
Mendelian trait/disorder: yes
Considered a defect: yes
Key variant known: no
Species-specific description: This disorder has been created artificially by CRISPR/Cas9; it is a genetically-modified organism (GMO)
Associated gene:
| Symbol | Description | Species | Chr | Location | OMIA gene details page | Other Links |
|---|---|---|---|---|---|---|
| DAX1 | Macaca fascicularis | - | no genomic information (-..-) | DAX1 | Ensembl |
Reference
| 2015 | Kang, Y., Zheng, B., Shen, B., Chen, Y., Wang, L., Wang, J., Niu, Y., Cui, Y., Zhou, J., Wang, H., Guo, X., Hu, B., Zhou, Q., Sha, J., Ji, W., Huang, X. : |
| CRISPR/Cas9-mediated Dax1 knockout in the monkey recapitulates human AHC-HH. Hum Mol Genet 24:7255-64, 2015. Pubmed reference: 26464492 . DOI: 10.1093/hmg/ddv425. |
Edit History
- Created by Frank Nicholas on 18 Oct 2016