OMIA:002143-9615 : Macrothrombocytopenia in Canis lupus familiaris (dog)

Categories: Haematopoietic system phene

Links to MONDO diseases: No links.

Mendelian trait/disorder: unknown

Considered a defect: yes

Species-specific description: Hayakawa et al. (2018) provided the first report of this disorder in dogs, in 3 unrelated Akitas.

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing

Breed: Akita (Dog) (VBO_0200010).
Breeds in which the phene has been documented. For breeds in which a likely causal variant has been documented, see the variant table below

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2023). OMIA:002143-9615: Online Mendelian Inheritance in Animals (OMIA) [dataset].


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2023 Haginoya, S., Thomovsky, E.J., Johnson, P.A., Brooks, A.C. :
Clinical assessment of primary hemostasis: A review. Top Companion Anim Med :100818, 2023. Pubmed reference: 37673175. DOI: 10.1016/j.tcam.2023.100818.
2016 Hayakawa, S., Spangler, E.A., Christopherson, P.W., Boudreaux, M.K. :
A novel form of macrothrombocytopenia in Akita dogs. Vet Clin Pathol 45:103-5, 2016. Pubmed reference: 26927710. DOI: 10.1111/vcp.12331.

Edit History

  • Created by Frank Nicholas on 23 Mar 2018
  • Changed by Imke Tammen2 on 16 Oct 2023