OMIA 002148-9615 : Deafness, bilateral, and vestibular dysfunction in Canis lupus familiaris
|Symbol||Description||Species||Chr||Location||OMIA gene details page||Other Links|
|MYO7A||myosin VIIA||Canis lupus familiaris||21||NC_051825.1 (21823670..21739388)||MYO7A||Homologene, Ensembl, NCBI gene|
By default, variants are sorted chronologically by year of publication, to provide a historical perspective. Readers can re-sort on any column by clicking on the column header. Click it again to sort in a descending order. To create a multiple-field sort, hold down Shift while clicking on the second, third etc relevant column headers.
WARNING! Inclusion of a variant in this table does not automatically mean that it should be used for DNA testing. Anyone contemplating the use of any of these variants for DNA testing should examine critically the relevant evidence (especially in breeds other than the breed in which the variant was first described). If it is decided to proceed, the location and orientation of the variant sequence should be checked very carefully.
|Breed(s)||Variant Phenotype||Gene||Allele||Type of Variant||Reference Sequence||Chr.||g. or m.||c. or n.||p.||Verbal Description||EVA ID||Year Published||PubMed ID(s)||Acknowledgements|
|Doberman Pinscher||Deafness, bilateral, and vestibular dysfunction||MYO7A||missense||CanFam3.1||21||g.21563111G>A||c.3719G>A||p.R1240Q||2019||31097876|
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
|2019||Webb, A.A., Ruhe, A.L., Neff, M.W., Webb, A.A., Ruhe, A.L., Neff, M.W. :|
|A missense mutation in MYO7A is associated with bilateral deafness and vestibular dysfunction in the Doberman pinscher breed. Can J Vet Res 83:142-148, 2019. Pubmed reference: 31097876.|
|2012||Strain, G.M. :|
|Canine deafness. Vet Clin North Am Small Anim Pract 42:1209-24, 2012. Pubmed reference: 23122177. DOI: 10.1016/j.cvsm.2012.08.010.|
|1992||Wilkes, M.K., Palmer, A.C. :|
|Congenital Deafness and Vestibular Deficit in the Dobermann Journal of Small Animal Practice 33:218-224, 1992.|
- Created by Frank Nicholas on 19 Apr 2018
- Changed by Frank Nicholas on 19 Apr 2018
- Changed by Frank Nicholas on 22 May 2019