OMIA 002201-9913 : Abortion due to haplotype NH7, CAD-related in Bos taurus
|Symbol||Description||Species||Chr||Location||OMIA gene details page||Other Links|
|CAD||carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase||Bos taurus||11||NC_037338.1 (72414662..72393099)||CAD||Homologene, Ensembl, NCBI gene|
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WARNING! Inclusion of a variant in this table does not automatically mean that it should be used for DNA testing. Anyone contemplating the use of any of these variants for DNA testing should examine critically the relevant evidence (especially in breeds other than the breed in which the variant was first described). If it is decided to proceed, the location and orientation of the variant sequence should be checked very carefully.
|Breed(s)||Variant Phenotype||Gene||Allele||Type of Variant||Reference Sequence||Chr.||g. or m.||c. or n.||p.||Verbal Description||EVA ID||Year Published||PubMed ID(s)||Acknowledgements|
|Normande||Abortion due to haplotype NH7||CAD||missense||11||g.72399397T>C||p.Tyr452Cys||2019||31056337|
|2019||Mesbah-Uddin, M., Hoze, C., Michot, P., Barbat, A., Lefebvre, R., Boussaha, M., Sahana, G., Fritz, S., Boichard, D., Capitan, A., Mesbah-Uddin, M., Hoze, C., Michot, P., Barbat, A., Lefebvre, R., Boussaha, M., Sahana, G., Fritz, S., Boichard, D., Capitan, A. :|
|A missense mutation (p.Tyr452Cys) in the CAD gene compromises reproductive success in French Normande cattle. J Dairy Sci 102:6340-6356, 2019. Pubmed reference: 31056337. DOI: 10.3168/jds.2018-16100.|
- Created by Frank Nicholas on 04 Jun 2019
- Changed by Frank Nicholas on 04 Jun 2019
- Changed by Frank Nicholas on 15 May 2020