OMIA:002212-9986 : Cardiomyopathy, hypertrophic, MYH7-related in Oryctolagus cuniculus

In other species: domestic cat , pig

Categories: Cardiovascular system phene

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 192600 (trait) , 160760 (gene) , 613426 (trait)

Links to MONDO diseases: No links.

Mendelian trait/disorder: yes

Considered a defect: yes

Key variant known: no

Inheritance: Transgenic model of human disease (GMO)

Associated gene:

Symbol Description Species Chr Location OMIA gene details page Other Links
MYH7 myosin, heavy chain 7, cardiac muscle, beta Oryctolagus cuniculus 17 NC_067390.1 (44530220..44509299) MYH7 Homologene, Ensembl , NCBI gene


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2022 Hornyik, T., Rieder, M., Castiglione, A., Major, P., Baczko, I., Brunner, M., Koren, G., Odening, K.E. :
Transgenic rabbit models for cardiac disease research. Br J Pharmacol 179:938-957, 2022. Pubmed reference: 33822374 . DOI: 10.1111/bph.15484.
2005 Senthil, V., Chen, S.N., Tsybouleva, N., Halder, T., Nagueh, S.F., Willerson, J.T., Roberts, R., Marian, A.J. :
Prevention of cardiac hypertrophy by atorvastatin in a transgenic rabbit model of human hypertrophic cardiomyopathy. Circ Res 97:285-92, 2005. Pubmed reference: 16020756 . DOI: 10.1161/
1999 Marian, A.J., Wu, Y., Lim, D.S., McCluggage, M., Youker, K., Yu, Q.T., Brugada, R., DeMayo, F., Quinones, M., Roberts, R. :
A transgenic rabbit model for human hypertrophic cardiomyopathy. J Clin Invest 104:1683-92, 1999. Pubmed reference: 10606622 . DOI: 10.1172/JCI7956.

Edit History

  • Created by Imke Tammen2 on 21 Apr 2021
  • Changed by Imke Tammen2 on 21 Apr 2021