OMIA:002277-64176 : Skin colour, orange/red in Podarcis muralis (common wall lizard)
Categories: Pigmentation phene
Links to MONDO diseases: No links.
Mendelian trait/disorder: yes
Mode of inheritance: Autosomal recessive
Considered a defect: no
Key variant known: no
Inheritance: Andrade et al. (2019): "in 56 of 57 cases, orange and mosaic individuals were homozygous for one allele (hereafter o) at the SPR locus, whereas yellow and white individuals, with one exception, were either heterozygous (n = 41) or homozygous (n = 16) for the alternative allele (hereafter O): a highly significant association (recessive model, P = 9.3 × 10−29)."
Molecular basis: Andrade et al. (2019): "The signal of association for orange coloration was restricted to a noncoding region immediately upstream of SPR"
|Symbol||Description||Species||Chr||Location||OMIA gene details page||Other Links|
|SPR||Podarcis muralis||9||NC_041320.1 (77997231..77994295)||SPR||Homologene, Ensembl , NCBI gene|
Cite this entry
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
|2023||Amer, A., Spears, S., Vaughn, P.L., Colwell, C., Livingston, E.H., McQueen, W., Schill, A., Reichard, D.G., Gangloff, E.J., Brock, K.M. :|
|Physiological phenotypes differ among color morphs in introduced common wall lizards (Podarcis muralis). Integr Zool :, 2023. Pubmed reference: 37884464 . DOI: 10.1111/1749-4877.12775.|
|2021||Andrade, P., Carneiro, M. :|
|Pterin-based pigmentation in animals. Biol Lett 17:20210221, 2021. Pubmed reference: 34403644 . DOI: 10.1098/rsbl.2021.0221.|
|2019||Andrade, P., Pinho, C., Pérez I de Lanuza, G., Afonso, S., Brejcha, J., Rubin, C.J., Wallerman, O., Pereira, P., Sabatino, S.J., Bellati, A., Pellitteri-Rosa, D., Bosakova, Z., Bunikis, I., Carretero, M.A., Feiner, N., Marsik, P., Paupério, F., Salvi, D., Soler, L., While, G.M., Uller, T., Font, E., Andersson, L., Carneiro, M. :|
|Regulatory changes in pterin and carotenoid genes underlie balanced color polymorphisms in the wall lizard. Proc Natl Acad Sci U S A 116:5633-5642, 2019. Pubmed reference: 30819892 . DOI: 10.1073/pnas.1820320116.|
- Created by Frank Nicholas on 17 Jun 2020
- Changed by Frank Nicholas on 17 Jun 2020