In other species: pig , goat , sheep

Categories: Reproductive system phene

Links to possible relevant human trait(s) and/or gene(s) in OMIM: 300247 (gene) , 300510 (trait)

Single-gene trait/disorder: yes

Disease-related: yes

Key variant known: no

Species summary: Crespo et al. (2024) used CRISPR/Cas9 technology to generate bmp15 mutants in Atlantic salmon: "results show that Bmp15 is required for proper follicle recruitment and growth and later ovulatory success in Atlantic salmon, providing an alternative candidate target to induce sterility in farmed salmon." This phene includes references to studies involving gene edited or genetically modified organisms (GMO).

Genetic engineering: Yes - variants have been created artificially, e.g. by genetic engineering or gene editing
Have human generated variants been created, e.g. through genetic engineering and gene editing

Associated gene: