OMIA 002307-9913 : Frontonasal dysplasia in Bos taurus
|Symbol||Description||Species||Chr||Location||OMIA gene details page||Other Links|
|ZIC2||Zic family member 2||Bos taurus||12||NC_037339.1 (76738347..76742927)||ZIC2||Homologene, Ensembl, NCBI gene|
By default, variants are sorted chronologically by year of publication, to provide a historical perspective. Readers can re-sort on any column by clicking on the column header. Click it again to sort in a descending order. To create a multiple-field sort, hold down Shift while clicking on the second, third etc relevant column headers.
WARNING! Inclusion of a variant in this table does not automatically mean that it should be used for DNA testing. Anyone contemplating the use of any of these variants for DNA testing should examine critically the relevant evidence (especially in breeds other than the breed in which the variant was first described). If it is decided to proceed, the location and orientation of the variant sequence should be checked very carefully.
Since October 2021, OMIA includes a semiautomated lift-over pipeline to facilitate updates of genomic positions to a recent reference genome position. These changes to genomic positions are not always reflected in the ‘acknowledgements’ or ‘verbal description’ fields in this table.
|OMIA Variant ID||Breed(s)||Variant Phenotype||Gene||Allele||Type of Variant||Source of Genetic Variant||Reference Sequence||Chr.||g. or m.||c. or n.||p.||Verbal Description||EVA ID||Inferred EVA rsID||Year Published||PubMed ID(s)||Acknowledgements|
|1283||Limousin||Frontonasal dysplasia||ZIC2||deletion, small (<=20)||Naturally occurring variant||ARS-UCD1.2||12||g.76742067del||rs3423095151||2021||33388042|
|2021||Braun, M., Lehmbecker, A., Eikelberg, D., Hellige, M., Beineke, A., Metzger, J., Distl, O. :|
|De novo ZIC2 frameshift variant associated with frontonasal dysplasia in a Limousin calf. BMC Genomics 22:1, 2021. Pubmed reference: 33388042. DOI: 10.1186/s12864-020-07350-y.|
- Created by Frank Nicholas on 24 Jan 2021
- Changed by Frank Nicholas on 24 Jan 2021