OMIA 002308-9986 : cardiomyopathy, X-linked dilated in Oryctolagus cuniculus |
Possibly relevant human trait(s) and/or gene(s)s (MIM numbers):
300377
,
302045
Mendelian trait/disorder:
yes
Mode of inheritance:
X-linked
Considered a defect:
yes
Key variant known:
no
Molecular basis:
The affected rabbits described by Liu et al. (2018) are generated by genome editing and are considered genetically-modified organisms (GMO).
Associated gene:
| Symbol | Description | Species | Chr | Location | OMIA gene details page | Other Links |
|---|---|---|---|---|---|---|
| DMD | dystrophin | Oryctolagus cuniculus | X | NC_013690.1 (19369710..17253997) | DMD | Homologene, Ensembl, NCBI gene |
Reference
| 2018 | Liu, Z., Chen, M., Chen, S., Deng, J., Song, Y., Lai, L., Li, Z. : | |
| Highly efficient RNA-guided base editing in rabbit. Nat Commun 9:2717, 2018. Pubmed reference: 30006570. DOI: 10.1038/s41467-018-05232-2. |
Edit History
- Created by Imke Tammen2 on 26 Jan 2021
- Changed by Imke Tammen2 on 28 Jan 2021