OMIA 002308-9986 : Cardiomyopathy, X-linked dilated in Oryctolagus cuniculus |
Category: Cardiovascular system phene
Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 300377 (gene) , 302045 (trait)
Links to MONDO diseases: No links.
Mendelian trait/disorder: yes
Mode of inheritance: X-linked
Considered a defect: yes
Key variant known: no
Molecular basis: The affected rabbits described by Liu et al. (2018) are generated by genome editing and are considered genetically-modified organisms (GMO).
Associated gene:
| Symbol | Description | Species | Chr | Location | OMIA gene details page | Other Links |
|---|---|---|---|---|---|---|
| DMD | dystrophin | Oryctolagus cuniculus | X | NC_067395.1 (19495405..17243300) | DMD | Homologene, Ensembl, NCBI gene |
Reference
| 2018 | Liu, Z., Chen, M., Chen, S., Deng, J., Song, Y., Lai, L., Li, Z. : |
| Highly efficient RNA-guided base editing in rabbit. Nat Commun 9:2717, 2018. Pubmed reference: 30006570. DOI: 10.1038/s41467-018-05232-2. |
Edit History
- Created by Imke Tammen2 on 26 Jan 2021
- Changed by Imke Tammen2 on 28 Jan 2021