OMIA 002362-9925 : Fecundity, GDF9-related in Capra hircus

In other species: sheep , dog

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 601918 (gene) , 618014 (trait)

Mendelian trait/disorder: yes

Mode of inheritance: Autosomal

Considered a defect: no

Key variant known: yes

Year key variant first reported: 2016

Associated gene:

Symbol Description Species Chr Location OMIA gene details page Other Links
GDF9 growth differentiation factor 9 Capra hircus 7 NC_030814.1 (66023938..66028657) GDF9 Homologene, Ensembl, NCBI gene

References


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2021 Aboelhassan, D.M., Darwish, A.M., Ali, N.I., Ghaly, I.S., Farag, I.M. :
A study on mutation points of GDF9 gene and their association with prolificacy in Egyptian small ruminants. J Genet Eng Biotechnol 19:85, 2021. Pubmed reference: 34097165. DOI: 10.1186/s43141-021-00181-8.
2019 Ghoreishi, H., Fathi-Yosefabad, S., Shayegh, J., Barzegari, A. :
Identification of mutations in <i>BMP15</i> and <i>GDF9</i> genes associated with prolificacy of Markhoz goats. Arch Anim Breed 62:565-570, 2019. Pubmed reference: 31807668. DOI: 10.5194/aab-62-565-2019.
2018 Wang, X., Yang, Q., Wang, K., Yan, H., Pan, C., Chen, H., Liu, J., Zhu, H., Qu, L., Lan, X. :
Two strongly linked single nucleotide polymorphisms (Q320P and V397I) in GDF9 gene are associated with litter size in cashmere goats. Theriogenology 125:115-121, 2018. Pubmed reference: 30414564. DOI: 10.1016/j.theriogenology.2018.10.013.
2016 Zhao, J., Liu, S., Zhou, X., Zhang, R., Li, Y., Wang, X., Chen, Y. :
A non-synonymous mutation in GDF9 is highly associated with litter size in cashmere goats. Anim Genet 47:630-1, 2016. Pubmed reference: 27298140. DOI: 10.1111/age.12447.

Edit History


  • Created by Imke Tammen2 on 25 Jun 2021
  • Changed by Imke Tammen2 on 25 Jun 2021