OMIA 002362-9940 : Fecundity, GDF9-related in Ovis aries

In other species: dog , goat

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 601918 (gene) , 618014 (trait)

Mendelian trait/disorder: yes

Mode of inheritance: Autosomal

Considered a defect: no

Key variant known: yes

Year key variant first reported: 2016

Species-specific description: Several other OMIA entries relate to specific variants in the GDF9 gene and their impact on fecundity: OMIA 001559-9940 Fecundity, Embrapa, FecG(E); OMIA 001961-9940 Fecundity, Vacaria, FecG(V); OMIA 001801-9940 Fecundity, High fertility, FecG(H); OMIA 001763-9940 Fecundity, Norwegian White Sheep; OMIA 000385-9940 Fecundity, Thoka, FecG(T)

Associated gene:

Symbol Description Species Chr Location OMIA gene details page Other Links
GDF9 growth differentiation factor 9 Ovis aries 5 NC_056058.1 (42116604..42113878) GDF9 Homologene, Ensembl, NCBI gene

References


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2021 Aboelhassan, D.M., Darwish, A.M., Ali, N.I., Ghaly, I.S., Farag, I.M. :
A study on mutation points of GDF9 gene and their association with prolificacy in Egyptian small ruminants. J Genet Eng Biotechnol 19:85, 2021. Pubmed reference: 34097165. DOI: 10.1186/s43141-021-00181-8.
Çelikeloğlu, K., Tekerli, M., Erdoğan, M., Koçak, S., Hacan, Ö., Bozkurt, Z. :
An investigation of the effects of BMPR1B, BMP15, and GDF9 genes on litter size in Ramlıç and Dağlıç sheep. Arch Anim Breed 64:223-230, 2021. Pubmed reference: 34159253. DOI: 10.5194/aab-64-223-2021.
2016 Khodabakhshzadeh, R., Mohammadabadi, M.R., Esmailizadeh, A.K., Moradi Shahrebabak, H., Bordbar, F., Ansari Namin, S. :
Identification of point mutations in exon 2 of GDF9 gene in Kermani sheep. Pol J Vet Sci 19:281-9, 2016. Pubmed reference: 27487501. DOI: 10.1515/pjvs-2016-0035.
2005 Chu, MX., Sang, LH., Wang, JY., Fang, L., Ye, SC. :
[Study on BMP15 and GDF9 as candidate genes for prolificacy of Small Tail Han sheep] Yi Chuan Xue Bao 32:38-45, 2005. Pubmed reference: 15715436.

Edit History


  • Created by Imke Tammen2 on 25 Jun 2021
  • Changed by Imke Tammen2 on 25 Jun 2021
  • Changed by Imke Tammen2 on 01 Jul 2021