OMIA 002379-9483 : Parkinson disease, LRRK2-realted in Callithrix jacchus

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 609007 (gene) , 607060 (trait)

Mendelian trait/disorder: unknown

Considered a defect: yes

Species-specific description: This study involves genetically modified organisms (GMO).

Reference


2020 Vermilyea, S.C., Babinski, A., Tran, N., To, S., Guthrie, S., Kluss, J.H., Schmidt, J.K., Wiepz, G.J., Meyer, M.G., Murphy, M.E., Cookson, M.R., Emborg, M.E., Golos, T.G. :
In vitro CRISPR/Cas9-directed gene editing to model LRRK2 G2019S Parkinson's disease in common marmosets. Sci Rep 10:3447, 2020. Pubmed reference: 32103062. DOI: 10.1038/s41598-020-60273-2.

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  • Created by Imke Tammen2 on 11 Aug 2021