OMIA 002426-10042 : Coat colour, dominant spot in Peromyscus maniculatus

Mendelian trait/disorder: yes

Mode of inheritance: Autosomal Dominant

Considered a defect: yes

Key variant known: no

Inheritance: S/S homozygotes are likely embryonic lethal

Mapping: Shang et al. (2020) "conduct a candidate gene linkage analysis for the Dominant spot trait and determined that Dominant spot is linked to a region of chromosome 20 that contains a strong candidate gene, Sox10. During the linkage analysis, we found that the spot size varied quantitively in affected Peromyscus based on genetic background."


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2020 Shang, Z., Horovitz, D.J., McKenzie, R.H., Keisler, J.L., Felder, M.R., Davis, S.W. :
Using genomic resources for linkage analysis in Peromyscus with an application for characterizing Dominant Spot. BMC Genomics 21:622, 2020. Pubmed reference: 32912160. DOI: 10.1186/s12864-020-06969-1.
2013 Vrana, P.B., Shorter, K.R., Szalai, G., Felder, M.R., Crossland, J.P., Veres, M., Allen, J.E., Wiley, C.D., Duselis, A.R., Dewey, M.J., Dawson, W.D. :
Peromyscus (deer mice) as developmental models. Wiley Interdiscip Rev Dev Biol 3:211-30, 2013. Pubmed reference: 24896658. DOI: 10.1002/wdev.132.
1936 Feldman, H.W. :
Piebald characters of the deer mouse. J Heredity 27:301, 1936.

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  • Created by Imke Tammen2 on 16 Sep 2021
  • Changed by Imke Tammen2 on 16 Sep 2021