OMIA 002544-9823 : GAPO syndrome in Sus scrofa

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 230740 (trait) , 606410 (gene)

Mendelian trait/disorder: unknown

Considered a defect: yes

Species-specific name: This phene was created by CRISPR/Cas9 genome editing, i.e. affected pigs are genetically-modified organisms (GMO)

Associated gene:

Symbol Description Species Chr Location OMIA gene details page Other Links
ANTXR1 anthrax toxin receptor 1 Sus scrofa 3 NC_010445.4 (73398379..73157744) ANTXR1 Homologene, Ensembl, NCBI gene

Reference


2022 Chen, P.R., Rowland, R.R.R., Stoian, A.M., Petrovan, V., Sheahan, M., Ganta, C., Cino-Ozuna, G., Kim, D.Y., Dunleavey, J.M., Whitworth, K.M., Samuel, M.S., Spate, L.D., Cecil, R.F., Benne, J.A., Yan, X., Fang, Y., Croix, B.S., Lechtenberg, K., Wells, K.D., Prather, R.S. :
Disruption of anthrax toxin receptor 1 in pigs leads to a rare disease phenotype and protection from senecavirus A infection. Sci Rep 12:5009, 2022. Pubmed reference: 35322150. DOI: 10.1038/s41598-022-09123-x.

Edit History


  • Created by Frank Nicholas on 26 Mar 2022