OMIA 002570-38626 : Chlamydia infection, susceptibility to in Phascolarctos cinereus

Mendelian trait/disorder: no

Mode of inheritance: Multifactorial

Considered a defect: yes

Key variant known: no

Inheritance: Cristescu et al. (2022) "investigated the genetic basis of variation in susceptibility to chlamydia ... . We combined data from veterinary examinations, chlamydia testing, genetic sampling and movement monitoring. Out of our sample of 342 wild koalas, 60 were found to have chlamydia. Using genotype information on 5007 SNPs to investigate the role of genetic variation in determining disease status, we found no evidence of inbreeding depression, but a heritability of 0.11 (95%CI = 0.06 - 0.23) for the probability that koalas had chlamydia."

Reference


2022 Cristescu, R.H., Strickland, K., Schultz, A.J., Kruuk, L.E.B., de Villiers, D., Frère, C.H. :
Susceptibility to a sexually transmitted disease in a wild koala population shows heritable genetic variance but no inbreeding depression. Mol Ecol :, 2022. Pubmed reference: 36043238. DOI: 10.1111/mec.16676.

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  • Created by Imke Tammen2 on 11 Sep 2022