OMIA 002599-9615 : Iris sphincter dysplasia in Canis lupus familiaris

Category: Vision / eye phene

Links to MONDO diseases: No links.

Mendelian trait/disorder: unknown

Considered a defect: yes

Species-specific symbol: ISD

Species-specific description: Genetics Committee of the American College of Veterinary Opthalmologists: "Defective development of the iris, or part of the iris, resulting in an immature state. ISD [Iris sphincter dysplasia] is the result of poorly developed iris sphincter muscles. The pupils of dogs with ISD do not properly contract in bright light. Dogs usually are uncomfortable and often squint in sunlight. The disorder exposes the interior of the eye to ultraviolet light that may potentially cause serious vision problems, such as cataracts or retinal damage, as dogs age."

Breed: Dalmatian.

Reference

2015 Genetics Committee of the American College of Veterinary Ophthalmologists :
Ocular Disorders Presumed to be Inherited in Purebred Dogs (“The Blue Book”), 8th edition :354-356, 2015.

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  • Created by Imke Tammen2 on 17 Nov 2022