OMIA:002599-9615 : Iris sphincter dysplasia in Canis lupus familiaris (dog) |
Categories: Vision / eye phene
Single-gene trait/disorder: unknown
Disease-related: yes
Species-specific symbol: ISD
Species-specific description: Genetics Committee of the American College of Veterinary Opthalmologists 2015): "Defective development of the iris, or part of the iris, resulting in an immature state. ISD [Iris sphincter dysplasia] is the result of poorly developed iris sphincter muscles. The pupils of dogs with ISD do not properly contract in bright light. Dogs usually are uncomfortable and often squint in sunlight. The disorder exposes the interior of the eye to ultraviolet light that may potentially cause serious vision problems, such as cataracts or retinal damage, as dogs age."
Breed:
Dalmatian (Dog) (VBO_0200427).
Breeds in which the phene has been documented. (If a likely causal variant has been documented for the phene, see the variant table breeds in which the variant has been reported).
Cite this entry
Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2023). OMIA:002599-9615: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2021 | Genetics Committee of the American College of Veterinary Opthalmologists : |
The Blue Book: Ocular disorders presumed to be inherited in purebred dogs. 13th Edition https://ofa.org/wp-content/uploads/2022/10/ACVO-Blue-Book-2021.pdf , 2021. | |
2015 | Genetics Committee of the American College of Veterinary Ophthalmologists : |
Ocular Disorders Presumed to be Inherited in Purebred Dogs (“The Blue Book”), 8th edition :354-356, 2015. |
Edit History
- Created by Imke Tammen2 on 17 Nov 2022
- Changed by Imke Tammen2 on 17 Jun 2023