OMIA:002648-9541 : Circadian disruption, BMAL1-related in Macaca fascicularis

Categories: Homeostasis / metabolism phene

Possibly relevant human trait(s) and/or gene(s) (MIM number): 602550 (gene)

Links to MONDO diseases: No links.

Mendelian trait/disorder: yes

Considered a defect: yes

Key variant known: yes

Species-specific description: This phene includes references to studies involving gene edited or genetically modified organisms (GMO).

Associated gene:

Symbol Description Species Chr Location OMIA gene details page Other Links
ARNTL aryl hydrocarbon receptor nuclear translocator like Macaca fascicularis 14 NC_052268.1 (73665169..73746067) ARNTL Homologene, Ensembl , NCBI gene


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2023 Yang, Y., Yu, P., Lu, Y., Gao, C., Sun, Q. :
Disturbed rhythmicity of intestinal hydrogen peroxide alters gut microbial oscillations in BMAL1-deficient monkeys. Cell Rep 42:112183, 2023. Pubmed reference: 36857177 . DOI: 10.1016/j.celrep.2023.112183.
2019 Liu, Z., Cai, Y., Liao, Z., Xu, Y., Wang, Y., Wang, Z., Jiang, X., Li, Y., Lu, Y., Nie, Y., Zhang, X., Li, C., Bian, X., Poo, M.M., Chang, H.C., Sun, Q. :
Cloning of a gene-edited macaque monkey by somatic cell nuclear transfer. Natl Sci Rev 6:101-108, 2019. Pubmed reference: 34691835 . DOI: 10.1093/nsr/nwz003.
Qiu, P., Jiang, J., Liu, Z., Cai, Y., Huang, T., Wang, Y., Liu, Q., Nie, Y., Liu, F., Cheng, J., Li, Q., Tang, Y.C., Poo, M.M., Sun, Q., Chang, H.C. :
BMAL1 knockout macaque monkeys display reduced sleep and psychiatric disorders. Natl Sci Rev 6:87-100, 2019. Pubmed reference: 34691834 . DOI: 10.1093/nsr/nwz002.

Edit History

  • Changed by Imke Tammen2 on 09 Mar 2023
  • Created by Imke Tammen2 on 09 Mar 2023