OMIA:002665-9031 : Genetically engineered humanized animal in Gallus gallus (chicken) |
In other species: crab-eating macaque , Rhesus monkey , pig , taurine cattle , goat
Categories: Immune system phene
Mendelian trait/disorder: unknown
Disease-related: unknown
Species-specific description: Yoo et al. (2024) showed that genome-edited chickens can be an efficient platform for producing multimeric recombinant human adiponectin (ADPN). This study involves genetically modified organisms (GMO).
Genetic engineering:
Yes - variants have been created artificially, e.g. by genetic engineering or gene editing
Have human generated variants been created, e.g. through genetic engineering and gene editing
Cite this entry
Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2024). OMIA:002665-9031: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
| 2024 | Xu, J., Ren, J., Xu, K., Fang, M., Ka, M., Xu, F., Wang, X., Wang, J., Han, Z., Feng, G., Zhang, Y., Hai, T., Li, W., Hu, Z. : |
| Elimination of GGTA1, CMAH, β4GalNT2 and CIITA genes in pigs compromises human versus pig xenogeneic immune reactions. Animal Model Exp Med 7:584-590, 2024. Pubmed reference: 38962826. DOI: 10.1002/ame2.12461. | |
| Yoo, E., Choi, H.J., Kim, J.K., Kim, Y.M., Park, J.S., Han, J.Y. : | |
| Sustainable production of multimeric and functional recombinant human adiponectin using genome-edited chickens. J Biol Eng 18:32, 2024. Pubmed reference: 38715027. DOI: 10.1186/s13036-024-00427-2. |
Edit History
- Created by Imke Tammen2 on 14 May 2024
- Changed by Imke Tammen2 on 14 May 2024