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OMIA:002665-9925 : Genetically engineered humanized animal in Capra hircus (goat)

In other species: chicken , crab-eating macaque , Rhesus monkey , pig , taurine cattle

Categories: Immune system phene

Single-gene trait/disorder: unknown

Disease-related: no

Species-specific description: This phene includes references to studies involving gene edited or genetically modified organisms (GMO).

Genetic engineering: Yes - variants have been created artificially, e.g. by genetic engineering or gene editing
Have human generated variants been created, e.g. through genetic engineering and gene editing

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2023). OMIA:002665-9925: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70

References

Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2024 Li, D., Guo, R., Chen, F., Wang, J., Wang, F., Wan, Y. :
Genetically engineered goats as efficient mammary gland bioreactors for production of recombinant human neutrophil peptide 1 using CRISPR/Cas9. Biology (Basel) 13:367, 2024. Pubmed reference: 38927247. DOI: 10.3390/biology13060367.
2023 Yan, L., Wu, H., Guan, S., Ma, W., Fu, Y., Ji, P., Lian, Z., Zhang, L., Xing, Y., Wang, B., Liu, G. :
The effects of mammary gland ATIII overexpression on the general health of dairy goats and their anti-inflammatory response to LPS stimulation. Int J Mol Sci 24:15303, 2023. Pubmed reference: 37894983. DOI: 10.3390/ijms242015303.
2008 Zou, X., Yuan, S., Xian, J., Zhao, Y., Li, D., Wang, Y., Hao, R., Jie, J., Liu, S., Du, M. :
Large scale production of recombinant human antithrombin Il(rhATI) in transgenic cloned goats. (In Chinese) Chin. J. Biotechnol. 109:117–123, 2008. DOI: 10.13345/j.cjb.2008.01.013.

Edit History


  • Created by Imke Tammen2 on 05 Nov 2023
  • Changed by Imke Tammen2 on 05 Nov 2023
  • Changed by Imke Tammen2 on 10 Dec 2023