OMIA:002670-9793 : Lactoglobulin, beta in Equus asinus (ass (donkey))
Links to MONDO diseases: No links.
Mendelian trait/disorder: yes
Considered a defect: no
Key variant known: no
Year key variant first reported: 2023
Species-specific description: Cosenza et al. (2023) "report the whole nucleotide sequence of the BLG I [LOC106829109] gene from 2 donkeys, whose milk samples are characterized by the β-LG I [beta lactoglobulin] SDS-PAGE band with a normal electrophoretic mobility ..., and by the presence of a unique β-LG I band with a higher electrophoretic mobility ... . A high genetic variability was found all over the 2 sequenced BLG I alleles." Based on their sequencing results and publicly available information the authors "deduce at least 5 different alleles (BLG I A, B, B1, C, D) responsible for 4 potential β-LG I translations."
Have human generated variants been created, e.g. through genetic engineering and gene editing
|Symbol||Description||Species||Chr||Location||OMIA gene details page||Other Links|
|LOC106829109||beta-lactoglobulin-1||Equus asinus||10||NC_052186.1 (8316754..8322198)||LOC106829109||Homologene, Ensembl , NCBI gene|
Cite this entry
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
|2023||Cosenza, G., Martin, P., Garro, G., Gallo, D., Auzino, B., Ciampolini, R., Pauciullo, A. :|
|A novel allelic donkey β-lactogobulin I protein isoform generated by a non-AUG translation initiation codon is associated with a nonsynonymous SNP. J Dairy Sci , 2023. Pubmed reference: 37080792. DOI: 10.3168/jds.2022-22598.|
|2022||Auzino, B., Miranda, G., Henry, C., Krupova, Z., Martini, M., Salari, F., Cosenza, G., Ciampolini, R., Martin, P. :|
|Top-Down proteomics based on LC-MS combined with cDNA sequencing to characterize multiple proteoforms of Amiata donkey milk proteins. Food Res Int 160:111611, 2022. Pubmed reference: 36076434. DOI: 10.1016/j.foodres.2022.111611.|
|2000||Herrouin, M., Mollé, D., Fauquant, J., Ballestra, F., Maubois, J.L., Léonil, J. :|
|New genetic variants identified in donkey's milk whey proteins. J Protein Chem 19:105-15, 2000. Pubmed reference: 10945434. DOI: 10.1023/a:1007078415595.|
|1988||Godovac-Zimmermann, J., Conti, A., James, L., Napolitano, L. :|
|Microanalysis of the amino-acid sequence of monomeric beta-lactoglobulin I from donkey (Equus asinus) milk. The primary structure and its homology with a superfamily of hydrophobic molecule transporters. Biol Chem Hoppe Seyler 369:171-9, 1988. Pubmed reference: 3370127. DOI: 10.1515/bchm3.1988.369.1.171.|
- Created by Imke Tammen2 on 22 Apr 2023
- Changed by Imke Tammen2 on 22 Apr 2023