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OMIA:002729-9615 : Thoracoabdominal syndrome in Canis lupus familiaris (dog)

Categories: Cardiovascular system phene , Embryo phene

Possibly relevant human trait(s) and/or gene(s) (MIM number): 313850 (trait)

Links to MONDO diseases: No links.

Mendelian trait/disorder: unknown

Considered a defect: yes

Cross-species summary: Ventral midline closure defect that is also called 'Pentalogy of Cantrell'. It involves defects of the thoracoabdominal wall as well as sternal, diaphragmatic, pericardial and cardiac malformations.

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing

Breed: Papillon (Dog) (VBO_0200985).
Breeds in which the phene has been documented. For breeds in which a likely causal variant has been documented, see the variant table below

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2023). OMIA:002729-9615: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70

Reference

2023 So, W., Donahoe, S.L., Podadera, J.M., Mazrier, H. :
Pentalogy of Cantrell in two neonate littermate puppies: A spontaneous animal model suggesting familial inheritance. Animals (Basel) 13, 2023. Pubmed reference: 37443889. DOI: 10.3390/ani13132091.

Edit History


  • Created by Imke Tammen2 on 17 Jul 2023