OMIA:002733-7998 : Omega-3 fatty acid content, increased in Ictalurus punctatus (channel catfish) |
Categories: Homeostasis / metabolism phene
Links to MONDO diseases: No links.
Mendelian trait/disorder: unknown
Considered a defect: no
Species-specific description: Coogan et al. (2023) used CRISPR/Cas9 technology to 'knock in' a masu salmon elongase gene into the channel catfish melanocortin-4 receptor (mc4r) gene site: "To our knowledge this is the first example of genome engineering to simultaneously target transgenesis and knock-out a gene in a commercially important aquaculture species for multiple improved performance traits. With a high transgene integration rate, improved growth, and higher omega-3 fatty acid content, the use of ... transgenic channel catfish appears beneficial for application on commercial farms." (GMO)
Genetic engineering:
Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing
Cite this entry
Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2023). OMIA:002733-7998: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70
Reference
| 2023 | Coogan, M., Xing, D., Su, B., Alston, V., Johnson, A., Khan, M., Khalil, K., Elaswad, A., Li, S., Wang, J., Lu, C., Wang, W., Hettiarachchi, D., Shang, M., Hasin, T., Qin, Z., Cone, R., Butts, I.A.E., Dunham, R.A. : |
| CRISPR/Cas9-mediated knock-in of masu salmon (Oncorhyncus masou) elongase gene in the melanocortin-4 (mc4r) coding region of channel catfish (Ictalurus punctatus) genome. Transgenic Res , 2023. Pubmed reference: 37468714. DOI: 10.1007/s11248-023-00346-w. |
Edit History
- Created by Imke Tammen2 on 21 Jul 2023
- Changed by Imke Tammen2 on 21 Jul 2023