OMIA:002764-8839 : Beak colour, MITF-related in Anas platyrhynchos (Mallard)
Categories: Pigmentation phene
Possibly relevant human trait(s) and/or gene(s) (MIM number): 156845 (gene)
Links to MONDO diseases: No links.
Mendelian trait/disorder: yes
Considered a defect: no
Key variant known: no
Markers: Pan et al. (2023) analysed "genomic selection signatures to identify a candidate site associated with beak color. [The authors] ... used black-billed (Yiyang I meat duck synthetic line H1, H2, H3&HF) and yellow-billed ducks (Cherry Valley ducks and white feather Putian black duck). Quantitative real-time PCR and genotyping approaches were used to verify the function of the candidate site." MITF was selected as a candidate gene for further analysis and "expression of MITF in the black duck beak tissue was significantly higher (p < 0.01) than that in the yellow beak group ... ." The authors concluded that the intronic MITF variant "ASM874695v1:10:g.17814522T > A could be selected as a marker site for the duck beak color phenotype."
Have human generated variants been created, e.g. through genetic engineering and gene editing
|Symbol||Description||Species||Chr||Location||OMIA gene details page||Other Links|
|MITF||microphthalmia-associated transcription factor||Anas platyrhynchos||13||NC_051784.1 (5282692..5178923)||MITF||Homologene, Ensembl , NCBI gene|
Cite this entry
|2023||Pan, R., Hua, T., Guo, Q., Bai, H., Jiang, Y., Wang, Z., Bi, Y., Chen, G., Wu, X., Chang, G. :|
|Identification of SNPs in MITF associated with beak color of duck. Front Genet 14:1161396, 2023. Pubmed reference: 37671042. DOI: 10.3389/fgene.2023.1161396.|
- Created by Imke Tammen2 on 07 Sep 2023
- Changed by Imke Tammen2 on 07 Sep 2023