OMIA:002795-9940 : Claw/hoof colour in Ovis aries (sheep)
Categories: Pigmentation phene
Possibly relevant human trait(s) and/or gene(s) (MIM number): 156845 (gene)
Links to MONDO diseases: No links.
Mendelian trait/disorder: unknown
Considered a defect: no
Mapping: Su et al. (2023) "conducted a genome-wide association study (GWAS) analysis using restriction site associated DNA sequencing (RAD-seq) data from 577 Australian White sheep (black hoof color = 283, grey hoof color = 106, amber hoof color = 186) and performed association analysis utilizing the mixed linear model in EMMAX. The results of GWAS demonstrated that a specific single-nucleotide polymorphism (SNP; g. 33097911G>A) in intron 14 of the microphthalmia-associated transcription factor (MITF) gene was significantly associated with the hoof color in AUW sheep (p = 9.40 × 10−36)."
|Symbol||Description||Species||Chr||Location||OMIA gene details page||Other Links|
|MITF||microphthalmia-associated transcription factor||Ovis aries||19||NC_056072.1 (31911158..31673697)||MITF||Homologene, Ensembl , NCBI gene|
Cite this entry
|2023||Su, P., Wu, H., Huang, Y., Lu, X., Yin, J., Zhang, Q., Lan, X. :|
|The hoof color of Australian White sheep is associated with genetic variation of the MITF gene. Animals (Basel) 13:, 2023. Pubmed reference: 37893942 . DOI: 10.3390/ani13203218.|
- Created by Imke Tammen2 on 05 Nov 2023
- Changed by Imke Tammen2 on 05 Nov 2023