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Gene GGTA1 : glycoprotein, alpha-galactosyltransferase 1 in Sus scrofa

 See the equivalent entry at NCBI

Symbol: GGTA1

Synonyms: alpha1,3GT

Description: glycoprotein, alpha-galactosyltransferase 1

Type of gene: protein-coding

NCBI gene id: 396733

Other designations: N-acetyllactosaminide alpha-1,3-galactosyltransferase|UDP-galactose:beta-D-galactosyl-1,4-N-acetyl-D-glucosaminide alpha-1,3-galactosyltransferase|alpha-1,3-galactosyltransferase|galactosyltransferase|glycoprotein alpha-galactosyltransferase 1 (inactive) ??|glycoprotein alpha-galactosyltransferase 1, pseudogene

Links: Homologene , Ensembl

Genomic location: 1:261587968..261511304 [Chromosome accession NC_010443.5]

Related phenes:

OMIA:001089-9823 : Blood group system ABO in Sus scrofa

References


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2013 Bradstreet, R.W., Toledo-Pereyra, L.H. :
Mechanisms of Gal-knockout pig cell selection for somatic cell nuclear transfer. J Surg Res 186:107-8, 2013. Pubmed reference: 23499396. DOI: 10.1016/j.jss.2013.02.007.
Li, P., Estrada, J.L., Burlak, C., Tector, A.J. :
Biallelic knockout of the α-1,3 galactosyltransferase gene in porcine liver-derived cells using zinc finger nucleases. J Surg Res 181:e39-45, 2013. Pubmed reference: 22795272. DOI: 10.1016/j.jss.2012.06.035.
Liu, Y., Yang, J.Y., Lu, Y., Yu, P., Dove, C.R., Hutcheson, J.M., Mumaw, J.L., Stice, S.L., West, F.D. :
α-1,3-Galactosyltransferase Knockout Pig Induced Pluripotent Stem Cells: A Cell Source for the Production of Xenotransplant Pigs. Cell Reprogram 15:107-16, 2013. Pubmed reference: 23402576. DOI: 10.1089/cell.2012.0062.
Miyagawa, S., Maeda, A., Takeishi, S., Ueno, T., Usui, N., Matsumoto, S., Okitsu, T., Goto, M., Nagashima, H. :
A lectin array analysis for wild-type and α-Gal-knockout pig islets versus healthy human islets. Surg Today 43:1439-47, 2013. Pubmed reference: 23549931. DOI: 10.1007/s00595-013-0569-6.
Shimatsu, Y., Yamada, K., Horii, W., Hirakata, A., Sakamoto, Y., Waki, S., Sano, J., Saitoh, T., Sahara, H., Shimizu, A., Yazawa, H., Sachs, D.H., Nunoya, T. :
Production of cloned NIBS (Nippon Institute for Biological Science) and α-1, 3-galactosyltransferase knockout MGH miniature pigs by somatic cell nuclear transfer using the NIBS breed as surrogates. Xenotransplantation 20:157-64, 2013. Pubmed reference: 23581451. DOI: 10.1111/xen.12031.
2012 Burlak, C., Wang, Z.Y., Chihara, R.K., Lutz, A.J., Wang, Y., Estrada, J.L., Tector, A.J. :
Identification of human preformed antibody targets in GTKO pigs. Xenotransplantation 19:92-101, 2012. Pubmed reference: 22497511. DOI: 10.1111/j.1399-3089.2012.00695.x.
Ekser, B., Bianchi, J., Ball, S., Iwase, H., Walters, A., Ezzelarab, M., Veroux, M., Gridelli, B., Wagner, R., Ayares, D., Cooper, D.K. :
Comparison of hematologic, biochemical, and coagulation parameters in α1,3-galactosyltransferase gene-knockout pigs, wild-type pigs, and four primate species. Xenotransplantation 19:342-54, 2012. Pubmed reference: 23145497. DOI: 10.1111/xen.12007.
Fang, J., Walters, A., Hara, H., Long, C., Yeh, P., Ayares, D., Cooper, D.K., Bianchi, J. :
Anti-gal antibodies in α1,3-galactosyltransferase gene-knockout pigs. Xenotransplantation 19:305-10, 2012. Pubmed reference: 22970769. DOI: 10.1111/j.1399-3089.2012.00710.x.
2011 Ekser, B., Gridelli, B., Veroux, M., Cooper, D.K. :
Clinical pig liver xenotransplantation: how far do we have to go? Xenotransplantation 18:158-67, 2011. Pubmed reference: 21696445. DOI: 10.1111/j.1399-3089.2011.00642.x.
Hara, H., Koike, N., Long, C., Piluek, J., Roh, D.S., SundarRaj, N., Funderburgh, J.L., Mizuguchi, Y., Isse, K., Phelps, C.J., Ball, S.F., Ayares, D.L., Cooper, D.K. :
Initial in vitro investigation of the human immune response to corneal cells from genetically engineered pigs. Invest Ophthalmol Vis Sci 52:5278-86, 2011. Pubmed reference: 21596821. DOI: 10.1167/iovs.10-6947.
Thompson, P., Badell, I.R., Lowe, M., Cano, J., Song, M., Leopardi, F., Avila, J., Ruhil, R., Strobert, E., Korbutt, G., Rayat, G., Rajotte, R., Iwakoshi, N., Larsen, C.P., Kirk, A.D. :
Islet xenotransplantation using gal-deficient neonatal donors improves engraftment and function. Am J Transplant 11:2593-602, 2011. Pubmed reference: 21883917. DOI: 10.1111/j.1600-6143.2011.03720.x.
2008 Fujimura, T., Murakami, H., Kurome, M., Takahagi, Y., Shigehisa, T., Nagashima, H. :
Effects of recloning on the efficiency of production of alpha 1,3-galactosyltransferase knockout pigs. J Reprod Dev 54:58-62, 2008. Pubmed reference: 18094530. DOI: 10.1262/jrd.19110.
2002 Lai, L., Kolber-Simonds, D., Park, K.W., Cheong, H.T., Greenstein, J.L., Im, G.S., Samuel, M., Bonk, A., Rieke, A., Day, B.N., Murphy, C.N., Carter, D.B., Hawley, R.J., Prather, R.S. :
Production of alpha-1,3-galactosyltransferase knockout pigs by nuclear transfer cloning. Science 295:1089-92, 2002. Pubmed reference: 11778012. DOI: 10.1126/science.1068228.
1995 Strahan, K.M., Gu, F., Preece, A.F., Gustavsson, I., Andersson, L., Gustafsson, K. :
cDNA sequence and chromosome localization of pig alpha 1,3 galactosyltransferase. Immunogenetics 41:101-5, 1995. Pubmed reference: 7528726. DOI: 10.1007/BF00182319.