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Gene CTSD : cathepsin D in Ovis aries

 See the equivalent entry at NCBI

In other species: dog

Symbol: CTSD

Synonyms: CTSD

Description: cathepsin D

Type of gene: protein-coding

NCBI gene id: 443060

Other designations: cathepsin D|lysosomal aspartyl protease

Links: Homologene , Ensembl

Genomic location: 21:46088585..46097887 [Chromosome accession NC_056074.1]

Related phenes:

OMIA:001505-9940 : Neuronal ceroid lipofuscinosis, 10 in Ovis aries

References


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2002 Palmer, DN., Oswald, MJ., Westlake, VJ., Kay, GW. :
The origin of fluorescence in the neuronal ceroid lipofuscinoses (Batten disease) and neuron cultures from affected sheep for studies of neurodegeneration. Arch Gerontol Geriatr 34:343-57, 2002. Pubmed reference: 14764335.
2001 Broom, MF., Zhou, C. :
Fine mapping of ovine ceroid lipofuscinosis confirms orthology with CLN6. Eur J Paediatr Neurol 5 Suppl A:33-5, 2001. Pubmed reference: 11589004.
Tammen, I., Cook, RW., Nicholas, FW., Raadsma, HW. :
Neuronal ceroid lipofuscinosis in Australian Merino sheep: a new animal model. Eur J Paediatr Neurol 5 Suppl A:37-41, 2001. Pubmed reference: 11589005. DOI: 10.1053/ejpn.2000.0432.
2000 Tyynelä, J., Sohar, I., Sleat, D.E., Gin, R.M., Donnelly, R.J., Baumann, M., Haltia, M., Lobel, P. :
A mutation in the ovine cathepsin D gene causes a congenital lysosomal storage disease with profound neurodegeneration EMBO Journal 19:2786-2792, 2000. Pubmed reference: 10856224. DOI: 10.1093/emboj/19.12.2786.
1999 Broom, MF., Zhou, C., Hill, DF. :
Progress toward positional cloning of ovine neuronal ceroid lipofuscinosis, a model of the human late-infantile variant CLN6. Mol Genet Metab 66:373-5, 1999. Pubmed reference: 10191131. DOI: 10.1006/mgme.1999.2823.
1996 Lane, SC., Jolly, RD., Schmechel, DE., Alroy, J., Boustany, RM. :
Apoptosis as the mechanism of neurodegeneration in Batten's disease. J Neurochem 67:677-83, 1996. Pubmed reference: 8764595.
1980 Jolly, RD., Janmaat, A., West, DM., Morrison, I. :
Ovine ceroid-lipofuscinosis: a model of Batten's disease. Neuropathol Appl Neurobiol 6:195-209, 1980. Pubmed reference: 6772982. DOI: 10.1111/j.1365-2990.1980.tb00290.x.
1976 Jolly, R. D., West, D. M. :
Blindness in South Hampshire sheep: a neuronal ceroid-lipofuscinosis New Zealand Veterinary Journal 24:123, 1976. Pubmed reference: 1067509. DOI: 10.1080/00480169.1976.34298.

Edit History


  • Changed by on 08 Apr 2015
  • Changed by Imke Tammen2 on 14 Nov 2023