OMIA 000044-9809 : Anencephaly/Exencephaly in Rhinoceros unicornis

In other species: cattle , sheep , Indo-pacific bottlenose dolphin

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 182940 (trait) , 206500 (trait) , 301410 (trait) , 619452 (trait)

Mendelian trait/disorder: unknown

Considered a defect: yes

Cross-species summary: Congenital absence of the cranial vault, with the cerebral hemispheres completely missing or reduced to small masses. This phene was originally called anencephaly, but a recent review suggested that the term anencephaly/exencephaly is more appropriate.

Species-specific description: A single rhinoceros fetus was described with partial anencephaly (aplasia of the cerebrum) and hypoplasia of the cerebellum (Schaftenaar et al., 2011).

References


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2021 Zarzycki, A., Thomas, Z.M., Mazrier, H. :
Comparison of inherited neural tube defects in companion animals and livestock. Birth Defects Res 113:319-348, 2021. Pubmed reference: 33615733. DOI: 10.1002/bdr2.1848.
2011 Schaftenaar, W., Fernandes, T., Fritsch, G., Frey, R., Szentiks, C.A., Wegner, R.D., Hildebrandt, T.B., Hermes, R. :
Dystocia and fetotomy associated with cerebral aplasia in a greater one-horned rhinoceros (Rhinoceros unicornis). Reprod Domest Anim 46:e97-101, 2011. Pubmed reference: 20412510. DOI: 10.1111/j.1439-0531.2010.01610.x.

Edit History


  • Created by Hamutal Mazrier on 26 Jul 2021