OMIA 000155-10141 : C3 deficiency in Cavia porcellus
In other species: dog , rabbit Possibly relevant human trait(s) and/or gene(s) (MIM number): 613779 Mendelian trait/disorder: yes Considered a defect: yes Key variant known: no Cross-species summary: Complement component 3 consists of two chains, alpha and beta, linked covalently by disulphide bonds. In humans and mice (and therefore presumably in all mammals), the two chains are encoded by a single gene (the C3 gene).
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
|1994||Singer, L., Colten, H.R., Wetsel, R.A. :|
|Complement C3 deficiency: human, animal, and experimental models. Pathobiology 62:14-28, 1994. Pubmed reference: 8031472.|
|1993||Botto, M., Walport, M.J. :|
|Hereditary deficiency of C3 in animals and humans. Int Rev Immunol 10:37-50, 1993. Pubmed reference: 8340676.|
|1986||Burger, R., Gordon, J., Stevenson, G., Ramadori, G., Zanker, B., Hadding, U., Bitter-Suermann, D. :|
|An inherited deficiency of the third component of complement, C3, in guinea pigs. Eur J Immunol 16:7-11, 1986. Pubmed reference: 3512275. DOI: 10.1002/eji.1830160103.|
- Created by Frank Nicholas on 11 Oct 2011