OMIA:000157-9940 : Intervertebral disc disease in Ovis aries (sheep) |
In other species: crab-eating macaque , Rhesus monkey , dog , domestic cat , lion , tiger , horse , taurine cattle , rabbit
Categories: Skeleton phene (incl. short stature & teeth)
Links to MONDO diseases: No links.
Mendelian trait/disorder: unknown
Considered a defect: yes
Cross-species summary: Also known as calcification of intervertebral discs.
Species-specific description: Sheep models of intervertebral disc disease have been artificially created by creating lesions in the outer, anterior annulus.
Genetic engineering:
Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing
Cite this entry
Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2023). OMIA:000157-9940: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70
Reference
| 2023 | Alini, M., Diwan, A.D., Erwin, W.M., Little, C.B., Melrose, J. : |
| An update on animal models of intervertebral disc degeneration and low back pain: Exploring the potential of artificial intelligence to improve research analysis and development of prospective therapeutics. JOR Spine 6:e1230, 2023. Pubmed reference: 36994457. DOI: 10.1002/jsp2.1230. |
Edit History
- Created by Imke Tammen2 on 31 Mar 2023
- Changed by Imke Tammen2 on 31 Mar 2023