In other species: chicken , king penguin , Adelie penguin , Humboldt's penguin , grivet , crab-eating macaque , dog , giant panda , domestic ferret , lion , ass (donkey) , domestic horse , taurine cattle , sheep , rabbit , domestic guinea pig , degu , gentoo penguin , Magellanic penguin , thirteen-lined ground squirrel , bald eagle , green monkey , Rockhopper penguin , chinstrap penguin , jackass penguin

Categories: Vision / eye phene

Single-gene trait/disorder: unknown

Disease-related: yes

Cross-species summary: Opacity of the lens of the eye.

Mapping: Bellamy et al. (2023) "performed a genome wide association study that included 57 controls and 27 + 23 + 7 cases of cortical-, anterior suture line- and posterior polar cataract, respectively. ... The study identified two loci, on CFA20 [BICF2S23632983] and CFA21 [BICF2G630640490], that were significantly associated with posterior polar cataract in Havanese. SNPs that showed putative association with cortical cataracts, were observed on CFA4 and CFA30. All the top SNPs are located in close proximity to cataract candidate genes."

Breeds: Bengal (Cat) (VBO_0100040), British Shorthair (Cat) (VBO_0100052), Domestic Shorthair (Cat) (VBO_0100119), Havana (Cat) (VBO_0100108), Himalayan (Cat) (VBO_0100117), Maine Coon (Cat) (VBO_0100154), Sphynx (Cat) (VBO_0100230).
Breeds in which the phene or likely causal variants have been documented. If a likely causal variant has been documented, see variant-specific breed information in the variant table. (Breed information may be incomplete).