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OMIA:000168-9685 : Cataract, generic in Felis catus (domestic cat)

In other species: chicken , grivet , crab-eating macaque , dog , giant panda , domestic ferret , lion , ass (donkey) , horse , taurine cattle , sheep , rabbit , domestic guinea pig , degu , thirteen-lined ground squirrel , bald eagle , green monkey

Categories: Vision / eye phene

Mendelian trait/disorder: unknown

Disease-related: yes

Cross-species summary: Opacity of the lens of the eye.

Mapping: Bellamy et al. (2023) "performed a genome wide association study that included 57 controls and 27 + 23 + 7 cases of cortical-, anterior suture line- and posterior polar cataract, respectively. ... The study identified two loci, on CFA20 [BICF2S23632983] and CFA21 [BICF2G630640490], that were significantly associated with posterior polar cataract in Havanese. SNPs that showed putative association with cortical cataracts, were observed on CFA4 and CFA30. All the top SNPs are located in close proximity to cataract candidate genes."

Breeds: Bengal (Cat) (VBO_0100040), Havana (Cat) (VBO_0100108), Himalayan (Cat) (VBO_0100117).
Breeds in which the phene has been documented. (If a likely causal variant has been documented for the phene, see the variant table breeds in which the variant has been reported).

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2023). OMIA:000168-9685: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70

References

Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2023 Bellamy, K.K.L., Lingaas, F. :
Cataracts in Havanese: genome wide association study reveals two loci associated with posterior polar cataract. Canine Med Genet 10:5, 2023. Pubmed reference: 37118843. DOI: 10.1186/s40575-023-00127-y.
2020 Kucharczyk, N., Cislo-Pakuluk, A., Stefanowicz, P., Bedford, P. :
Hereditary cataract in the Bengal cat in Poland. BMC Vet Res 16:293, 2020. Pubmed reference: 32799858. DOI: 10.1186/s12917-020-02517-x.
2019 Guyonnet, A., Donzel, E., Bourguet, A., Chahory, S. :
Epidemiology and clinical presentation of feline cataracts in France: A retrospective study of 268 cases. Vet Ophthalmol 22:116-124, 2019. Pubmed reference: 29508528. DOI: 10.1111/vop.12567.
2005 Glaze, M.B. :
Congenital and hereditary ocular abnormalities in cats. Clin Tech Small Anim Pract 20:74-82, 2005. Pubmed reference: 15948421. DOI: 10.1053/j.ctsap.2004.12.011.
1986 Rubin, L.F. :
Hereditary cataract in Himalayan cats Feline Practice 26:14-15, 1986.
1974 Peiffer, R.L., Gelatt, K.N. :
Cataracts in the cat Feline Practice 4:34-38, 1974.

Edit History


  • Created by Frank Nicholas on 06 Sep 2005
  • Changed by Imke Tammen2 on 12 Sep 2021
  • Changed by Imke Tammen2 on 01 May 2023