OMIA:000168-9685 : Cataract, generic in Felis catus
In other species: chicken , crab-eating macaque , dog , giant panda , domestic ferret , lion , ass , horse , cattle , sheep , rabbit , domestic guinea pig , degu , bald eagle ,
Categories: Vision / eye phene
Links to MONDO diseases: No links.
Mendelian trait/disorder: unknown
Considered a defect: yes
Cross-species summary: Opacity of the lens of the eye.
Mapping: Bellamy et al. (2023) "performed a genome wide association study that included 57 controls and 27 + 23 + 7 cases of cortical-, anterior suture line- and posterior polar cataract, respectively. ... The study identified two loci, on CFA20 [BICF2S23632983] and CFA21 [BICF2G630640490], that were significantly associated with posterior polar cataract in Havanese. SNPs that showed putative association with cortical cataracts, were observed on CFA4 and CFA30. All the top SNPs are located in close proximity to cataract candidate genes."
Breeds: Bengal (Cat) (VBO_0100040), Havana (Cat) (VBO_0100108), Himalayan (Cat) (VBO_0100117).
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
|2023||Bellamy, K.K.L., Lingaas, F. :|
|Cataracts in Havanese: genome wide association study reveals two loci associated with posterior polar cataract. Canine Med Genet 10:5, 2023. Pubmed reference: 37118843 . DOI: 10.1186/s40575-023-00127-y.|
|2020||Kucharczyk, N., Cislo-Pakuluk, A., Stefanowicz, P., Bedford, P. :|
|Hereditary cataract in the Bengal cat in Poland. BMC Vet Res 16:293, 2020. Pubmed reference: 32799858 . DOI: 10.1186/s12917-020-02517-x.|
|2019||Guyonnet, A., Donzel, E., Bourguet, A., Chahory, S. :|
|Epidemiology and clinical presentation of feline cataracts in France: A retrospective study of 268 cases. Vet Ophthalmol 22:116-124, 2019. Pubmed reference: 29508528 . DOI: 10.1111/vop.12567.|
|2005||Glaze, M.B. :|
|Congenital and hereditary ocular abnormalities in cats. Clin Tech Small Anim Pract 20:74-82, 2005. Pubmed reference: 15948421 . DOI: 10.1053/j.ctsap.2004.12.011.|
|1986||Rubin, L.F. :|
|Hereditary cataract in Himalayan cats Feline Practice 26:14-15, 1986.|
|1974||Peiffer, R.L., Gelatt, K.N. :|
|Cataracts in the cat Feline Practice 4:34-38, 1974.|
- Created by Frank Nicholas on 06 Sep 2005
- Changed by Imke Tammen2 on 12 Sep 2021
- Changed by Imke Tammen2 on 01 May 2023