OMIA:000243-9823 : Cryptorchidism in Sus scrofa (pig)

In other species: dog , domestic cat , puma , horse , Arabian camel , llama , taurine cattle , goat , sheep , domestic yak , alpaca

Categories: Reproductive system phene

Possibly relevant human trait(s) and/or gene(s) (MIM number): 219050 (trait)

Links to MONDO diseases:

Mendelian trait/disorder: unknown

Considered a defect: yes

Cross-species summary: Failure of one (unilateral) or both (bilateral) testes to descend.

Inheritance: Both unilateral and bilateral cryptorchidism are familial in pigs, but there is no convincing evidence for single-locus inheritance.

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2021). OMIA:000243-9823: Online Mendelian Inheritance in Animals (OMIA) [dataset].


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2023 da Silva, A.N., Ibelli, A.M.G., Savoldi, I.R., Cantão, M.E., Zanella, E.L., Marques, M.G., da Silva, M.V.G.B., de Peixoto, J.O., Ledur, M.C., Lopes, J.S., Vargas, J.E., Zanella, R. :
Whole-exome sequencing indicated new candidate genes associated with unilateral cryptorchidism in pigs. Sex Dev :1-11, 2023. Pubmed reference: 36758533. DOI: 10.1159/000528360.
2021 Chai, S., Huang, X., Wu, T., Xu, S., Ren, W., Yang, G. :
Comparative genomics reveals molecular mechanisms underlying health and reproduction in cryptorchid mammals. BMC Genomics 22:763, 2021. Pubmed reference: 34702182. DOI: 10.1186/s12864-021-08084-1.
2020 Yimpring, N., Roytrakul, S., Jaresitthikunchai, J., Phaonakrop, N., Krobthong, S., Suriyaphol, G. :
Proteomic profiles of unilateral cryptorchidism in pigs at different ages using MALDI-TOF mass spectrometry and in-gel digestion coupled with mass spectrometry (GeLC-MS/MS) approaches. BMC Vet Res 16:373, 2020. Pubmed reference: 33008399. DOI: 10.1186/s12917-020-02591-1.
2015 Sevillano, C.A., Lopes, M.S., Harlizius, B., Hanenberg, E.H., Knol, E.F., Bastiaansen, J.W. :
Genome-wide association study using deregressed breeding values for cryptorchidism and scrotal/inguinal hernia in two pig lines. Genet Sel Evol 47:18, 2015. Pubmed reference: 25886970. DOI: 10.1186/s12711-015-0096-6.
1999 Pinart, E., Sancho, S., Briz, M.D., Bonet, S., Badia, E. :
Efficiency of the process of meiosis in scrotal testes of healthy boars and unilateral abdominal cryptorchid boars Teratology 60:209-214, 1999. Pubmed reference: 10508974. DOI: 10.1002/(SICI)1096-9926(199910)60:4<209::AID-TERA5>3.0.CO;2-4.
Pinart, E., Sancho, S., Briz, M.D., Bonet, S., Garcia, N. :
Characterization of the semen quality of postpuberal boars with spontaneous unilateral abdominal cryptorchidism on the right side Animal Reproduction Science 55:269-278, 1999. Pubmed reference: 10379677.
1998 Hutson, J.M., Watts, L.M., Farmer, P.J. :
Congenital undescended testes in neonatal pigs and the effect of exogenous calcitonin gene-related peptide Journal of Urology 159:1025-1028, 1998. Pubmed reference: 9474224.
Pinart, E., Camps, R., Briz, M.D., Bonet, S., Egozcue, J. :
Unilateral spontaneous abdominal cryptorchidism - structural and ultrastructural study of sperm morphology Animal Reproduction Science 49:247-268, 1998. Pubmed reference: 9558443.
1996 Zhou, B.Y., Hutson, J.M., Hasthorpe, S. :
Histomorphometric study on germ cell differentiation of unilateral cryptorchidism in the immature pig Journal of Pediatric Surgery 31:1364-1366, 1996. Pubmed reference: 8906662.
1995 Anon. :
Castrating pigs with cryptorchidism. Tijdschrift Voor Diergeneeskunde 120:94, 1995.
Vandenbroeck, M., Maghuinrogister, G. :
Anatomo and histophysiological particularities of cryptorchidism: Unilateral cryptorchidism in the pig .2. Particular testicular developments associated with unilateral cryptorchidism in the pig Annales de Medecine Veterinaire 139:167-174, 1995.
Vandenbroeck, M., Maghuinrogister, G. :
Anatomo and histophysiological particularities of cryptorchidism: Unilateral cryptorchidism in the pig .1. A general introduction to unilateral cryptorchidism in the pig Annales de Medecine Veterinaire 139:157-163, 1995.
1992 Berger, B., Grabherr, H., Fischerleitner, F. :
Gene frequencies and phenotypical expression of some important hereditary defects in pigs as a basis for practical progeny testing. Wiener Tierarztliche Monatsschrift 79:212-214, 1992.
Stigler, J., Distl, O., Kruff, B., Krausslich, H. :
Studies of economically important congenital anomalies of pigs. Tierarztliche Umschau 47:883-886, 1992.
1991 Stigler, J., Distl, O., Kruff, B., Krausslich, H. :
Segregation analysis of hereditary defects in pigs. Zuchtungskunde 63:294-305, 1991.
1988 Althoff, W., Mayer, M., Richter, L., Simon, D. :
[Genetic causes of hernia and cryptorchidism in pigs] Zuchtungskunde 60:319-329, 1988.
Rothschild, M.F., Christian, L.L., Blanchard, W. :
Evidence for multigene control of cryptorchidism in swine Journal of Heredity 79:313-314, 1988. Pubmed reference: 2901444.
1987 Kraus, H., Schussler, R. :
[Ten-year analysis of anomalies recorded on boars at Neustadt] Zuchtwahl und Besamung :75-77, 1987.
1986 Cardenas Flores, C.A. :
[Frequency of cryptorchidism in pigs slaughtered at the ABC slaughterhouse] Veterinaria, Mexico 17:63 only, 1986.
Knap, P.W. :
Congenital defects inheritance of AI boars: genetic parameters and breeding value estimation procedures Livestock Production Science 15:337-352, 1986.
1984 Kobylka, V., Cerny, M., Hajkova, J. :
[Inherited abnormalities and defects in pedigreed herds of pigs in the Czech Republic in 1979-1983] Veterinarstvi 34:351-352, 1984.
1982 Ollivier, L., Sellier, P. :
Pig genetics: a review Annales de Genetique et de Selection Animale 14:481-544, 1982.
1979 Mikami, H., Fredeen, H.T. :
A genetic study of cryptorchidism and scrotal hernia in pigs Canadian Journal of Genetics and Cytology 21:9-19, 1979.
1977 Sittmann, K., Woodhouse, B. :
Sex linked and sex modified genetic defects in swine cryptorchidism Canadian Journal of Genetics and Cytology 19:487-502, 1977.
1971 Liptrap, R.M., Raeside, J.I. :
Urinary steroid excretion in response to endogenous and exogenous gonadetrophin stimulation of cryptorchid testes in the pig Journal of Reproduction and Fertility 25:55-60, 1971. Pubmed reference: 4396368.
1970 Liptrap, R.M., Raeside, J.I. :
Urinary steroid excretion in cryptorchidism in the pig Journal of Reproduction and Fertility 21:293-301, 1970. Pubmed reference: 4392653.
1963 Schulman, A. :
[Cryptorchidism in pigs in Finland] Finsk VetTidskr 69:349-358, 1963.
Wollrab, J., Lichtner, T. :
[On chromosomal sex determination in domestic animals and the behaviour of sex-specific nuclear appendages in neutrophiles of normal, cryptorchid and intersex pigs] Zuchthygiene, Fortpflanzungsstorungen und Besamung der Haustiere 7:241-253, 1963.
1962 Lichtner, T. :
[The behaviour of sex specific neutrophil nuclear appendages in the pig with reference to cryptorchids and intersexes] Wissenschaftliche Zeitschrift der Humboldt-Universitat zu Berlin, Mathematisch-Naturwissenschaftliche Reihe 1:210, 1962.
Nilsson, N.E. :
Cryptorchid boars and hermaphrodite pigs Svinskotsel. Svenska Svinavelsforenigens Tidskrift 52:189-190, 1962.
1934 McPhee, H.C., Buckley, S.S. :
Inheritance of cryptorchidism in swine Journal of Heredity 25:295-303, 1934.

Edit History

  • Created by Frank Nicholas on 06 Sep 2005
  • Changed by Imke Tammen2 on 16 Sep 2021