OMIA:000278-9031 : Diabetes insipidus in Gallus gallus (chicken)

In other species: dog , domestic cat , horse , pig , Japanese quail

Categories: Endocrine / exocrine gland phene (incl mammary gland)

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 125700 (trait) , 125800 (trait) , 221995 (trait) , 125800 (trait) , 222300 (trait) , 304800 (trait) , 304900 (trait)

Links to MONDO diseases: No links.

Mendelian trait/disorder: yes

Mode of inheritance: Autosomal recessive

Considered a defect: yes

Key variant known: no

Cross-species summary: Diabetes insipidus results from a deficiency of the antidiuretic hormone vasopressin (central diabetes insipidus) or from resistance to vasopressin (nephrogenic diabetes insipidus).

Species-specific symbol: di

History: This mutant line of chickens was first reported by Dunson and Buss (1968).

Inheritance: Dunson and Buss (1968) concluded that inheritance is autosomal recessive.

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2016). OMIA:000278-9031: Online Mendelian Inheritance in Animals (OMIA) [dataset].


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

1977 Obeidah, A., Mérat, P., Bordas, A. :
Polydipsia and polyuria at high environmental temperature in association with the productive traits in the fowl. Ann Genet Sel Anim 9:431-47, 1977. Pubmed reference: 22896545. DOI: 10.1186/1297-9686-9-4-431.
1976 Raffel, L.J., Buss, E.G., Clagett, C.O. :
Influence of arginine vasotocin on a genetically determined excessive appetite for water in chickens Poultry Science 55:1834-1840, 1976. Pubmed reference: 995808.
1970 Dunson, W.A., Buss, E.G. :
Hereditary diabetes insipidus in chickens Federation Proceedings 29:378 only, 1970.
1968 Dunson, W.A., Buss, E.G. :
Abnormal water balance in a mutant strain of chickens. Science 161:167-9, 1968. Pubmed reference: 5657064.

Edit History

  • Created by Frank Nicholas on 06 Sep 2005
  • Changed by Frank Nicholas on 26 Apr 2016