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OMIA:000383-9925 : Fecundity, BMPR1B-related in Capra hircus (goat)

In other species: sheep

Categories: Reproductive system phene

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 134720 (trait) , 609441 (trait) , 603248 (gene)

Links to MONDO diseases: No links.

Mendelian trait/disorder: unknown

Considered a defect: unknown

Species-specific description: Bi et al. (2021) investigated Fec B expression in six different goat tissues, and analyzed the effect of five potential copy number variations (CNVs) (CNV1-5) within the Fec B gene on litter size. The authors propose that CNV3 and CNV5 could serve as potential DNA molecular markers.

Jose et al. (2023) report creation of a FecB mutation into goat embryos using CRISPR technology (GMO).

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2023). OMIA:000383-9925: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70

References

Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2023 Jose, B., Punetha, M., Tripathi, M.K., Khanna, S., Yadav, V., Singh, A.K., Kumar, B., Singh, K., Chouhan, V.S., Sarkar, M. :
CRISPR/Cas mediated disruption of BMPR-1B gene and introduction of FecB mutation into the Caprine embryos using Easi-CRISPR strategy. Theriogenology 211:125-133, 2023. Pubmed reference: 37619525 . DOI: 10.1016/j.theriogenology.2023.08.008.
Song, T., Liu, Y., Cuomu, R., Tan, Y., A Wang, C., De, J., Cao, X., Zeng, X. :
Polymorphisms analysis of BMP15, GDF9 and BMPR1B in Tibetan Cashmere Goat (Capra hircus). Genes (Basel) 14:, 2023. Pubmed reference: 37239462 . DOI: 10.3390/genes14051102.
2021 Bi, Y., Feng, W., Kang, Y., Wang, K., Yang, Y., Qu, L., Chen, H., Lan, X., Pan, C. :
Detection of mRNA expression and copy number variations within the goat FecB gene associated with litter size. Front Vet Sci 8:758705, 2021. Pubmed reference: 34733908 . DOI: 10.3389/fvets.2021.758705.
2013 Pramod, R.K., Sharma, S.K., Singhi, A., Pan, S., Mitra, A. :
Differential ovarian morphometry and follicular expression of BMP15, GDF9 and BMPR1B influence the prolificacy in goat. Reprod Domest Anim 48:803-9, 2013. Pubmed reference: 23581245 . DOI: 10.1111/rda.12165.

Edit History


  • Created by Imke Tammen2 on 24 Nov 2021
  • Changed by Imke Tammen2 on 27 Aug 2023