OMIA 000387-9940 : Fecundity, Java in Ovis aries
Mendelian trait/disorder: yes Mode of inheritance: Autosomal Considered a defect: no Key variant known: no Species-specific description: Analysis of reproductive data from three breeds of Indonesian sheep (Javanese Thin Tail, Javanese Fat Tail, Semarang) produced substantial evidence for the presence of a gene of large effect on ovulation rate and litter size in all three breeds (Bradford et al., 1986). The difference between homozygotes was estimated to be 2.6 for ovulation rate and 1.8-2.0 for litter size. Since all three breeds are thought to have intermated from time to time, it was not considered surprising that apparently the same gene occurs in all three breeds. Davis et al. (2002) showed that this gene is actually the Booroola mutation, FecB(B) (see OMIA 000383-9940). They concluded "It is unknown whether Javanese Thin-tailed sheep acquired the Booroola gene directly from Garole sheep from India or via Merinos from Australia."
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
|2004||Souza, C.J., González-Bulnes, A., Campbell, B.K., McNeilly, A.S., Baird, D.T. :|
|Mechanisms of action of the principal prolific genes and their application to sheep production. Reprod Fertil Dev 16:395-401, 2004. Pubmed reference: 15315738. DOI: 10.10371/RD04038.|
|2000||Roberts, J.A. :|
|Frequency of the prolificacy gene in flocks of Indonesian thin tail sheep: a review [Review] Small Ruminant Research 36:215-226, 2000. Pubmed reference: 10781738.|
|1986||Bradford, G.E., Quirke, J.F., Sitorus, P., Inounu, I., Tiesnamurti, B., Bell, F.L., Fletcher, I.C., Torell, D.T. :|
|Reproduction in Javanese sheep: evidence for a gene with large effect on ovulation rate and litter size Journal of Animal Science 63:418-431, 1986. Pubmed reference: 3759678.|
- Created by Frank Nicholas on 06 Sep 2005
- Changed by Frank Nicholas on 04 May 2013