OMIA:000425-9940 : Haemonchus contortus, resistance to in Ovis aries (sheep) |
Categories: Immune system phene
Mendelian trait/disorder: unknown
Disease-related: no
Species-specific name: Golden ram effect
Species-specific description: In a large-scale investigation of the quantitative genetics of resistance and resiliance to Haemonchus contortus in Merino sheep, Albers et al. (1987) observed one 'outlier' sire (dubbed the "golden ram") whose progeny exhibited extremely high resistance. The evidence justified a tentative conclusion that this sire was carrying a major gene for resistance. Unfortunately, such a gene failed to materialise in studies of subsequent generations.
Cite this entry
Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2023). OMIA:000425-9940: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70
References
Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
| 2024 | Cunha, S.M.F., Willoughby, O., Schenkel, F., Cánovas, Á. : |
| Genetic parameter estimation and selection for resistance to gastrointestinal nematode parasites in sheep-a review. Animals (Basel) 14:613, 2024. Pubmed reference: 38396581. DOI: 10.3390/ani14040613. | |
| Kapritchkoff, R.T.I., Okino, C.H., Niciura, S.C.M., Bello, H.J.S., Matos, R.S., Melito, G.R., Bressani, F.A., Esteves, S.N., Chagas, A.C.S. : | |
| Association of β-globin polymorphisms and tolerance to haemonchosis in ewes and lambs of different sheep breeds. Vet Parasitol 328:S0304-4017(24)00051-7:110163, 2024. Pubmed reference: 38513446. DOI: 10.1016/j.vetpar.2024.110163. | |
| Pratap, R., Chennuru, S., Krovvidi, S., Chitithoti, J., Pentala, R.K. : | |
| Putative SNPs in Ovar-DRB1 and GALNTL6 genes conferring susceptibility to natural infection of Haemonchus contortus in Southern Indian sheep. Acta Parasitol 69:583-590, 2024. Pubmed reference: 38240996. DOI: 10.1007/s11686-023-00778-8. | |
| Thorne, J.W., Redden, R., Bowdridge, S.A., Becker, G.M., Khilji, S.F., Xie, S., Bentley, K.L., Murdoch, B.M. : | |
| Reducing fecal egg count through selective breeding alters dorper lamb response to Haemonchus contortus in an artificial challenge trial. Vet Parasitol 328:S0304-4017(24)00065-7:110177, 2024. Pubmed reference: 38583271. DOI: 10.1016/j.vetpar.2024.110177. | |
| 2023 | Okino, C.H., Niciura, S.C.M., Giaretta, P.R., Melito, G.R., Kapritchkoff, R.T.I., Santos, I.B.D., Rech, R.R., Minho, A.P., Esteves, S.N., Chagas, A.C.S. : |
| Enhanced mucosal response in sheep harbouring βA beta-globin against haemonchosis. Parasite Immunol 45:e13003, 2023. Pubmed reference: 37400087. DOI: 10.1111/pim.13003. | |
| Werne, S., Schwarz, K., Thüer, S., Bapst, B. : | |
| Breeding options for nematode resistance in Lacaune dairy sheep. Animal 17:100772, 2023. Pubmed reference: 37031576. DOI: 10.1016/j.animal.2023.100772. | |
| 1993 | Woolaston, R.R. : |
| Factors affecting the prevalence and severity of footrot in a Merino flock selected for resistance to Haemonchus contortus. Aust Vet J 70:365-9, 1993. Pubmed reference: 8257313. DOI: 10.1111/j.1751-0813.1993.tb00809.x. | |
| 1987 | Albers, G.A.A., Gray, G.D., Piper, L.R., Barker, J.S.F., Le Jambre, L.F., Barger, I.A. : |
| The genetics of resistance and resilience to Haemonchus contortus infection in young Merino sheep International Journal for Parasitology 17:1355-1363, 1987. Pubmed reference: 3429127. | |
| Gray, G.D. : | |
| Genetic resistance to haemonchosis in sheep Parasitology Today 3:253-255, 1987. |
Edit History
- Created by Frank Nicholas on 06 Sep 2005
- Changed by Frank Nicholas on 21 May 2012
- Changed by Frank Nicholas on 20 Aug 2020
- Changed by Imke Tammen2 on 23 Apr 2023