OMIA:000453-9940 : Hepatic encephalopathy in Ovis aries (sheep)

In other species: dog , domestic cat

Categories: Nervous system phene

Links to MONDO diseases: No links.

Mendelian trait/disorder: unknown

Considered a defect: yes

Cross-species summary: A degenerative disease of the brain induced by a failure of the liver to metabolise ammonia. Clinical signs include excitability, tremor, compulsive walking, head pressing, and apparent blindness, followed by coma and convulsions.

Genetic engineering: Unknown
Have human generated variants been created, e.g. through genetic engineering and gene editing

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2005). OMIA:000453-9940: Online Mendelian Inheritance in Animals (OMIA) [dataset].


1994 Clark, A.M., Spence, J.A. :
Possible familial hepatic encephalopathy in a Suffolk ewe Veterinary Record 135:463 only, 1994.

Edit History

  • Created by Frank Nicholas on 06 Sep 2005