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OMIA:000494-9615 : Hyperadrenocorticism, generic in Canis lupus familiaris (dog)

In other species: domestic ferret , domestic cat , horse , golden hamster

Categories: Endocrine / exocrine gland phene (incl mammary gland)

Links to possible relevant human trait(s) and/or gene(s) in OMIM: 169170 (trait) , 201710 (trait)

Mendelian trait/disorder: unknown

Disease-related: yes

Cross-species summary: Hyperadrenocorticism (or Cushing syndrome) refers to genetic and iatrogenic hypersecretion of adrenocorticotropic hormone (ACTH) (e.g. caused by tumours of either the pituitary or adrenal glands; or long-term administration of exogenous glucocorticoids). Entries for Cushing disease (pituitary-dependent hyperadrenocorticism) are included here and for some species also under the OMIA phene Cushing disease (OMIA:000247)

Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2023). OMIA:000494-9615: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70

References

Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2024 Hovious, K., Fowler, K., Beasly, M., Pancotto, T.E. :
Cushing's myopathy in dogs: Prevalence, clinical abnormalities, and response to treatment. Animals (Basel) 14:3109, 2024. Pubmed reference: 39518832. DOI: 10.3390/ani14213109.
2023 Bugbee, A., Rucinsky, R., Cazabon, S., Kvitko-White, H., Lathan, P., Nichelason, A., Rudolph, L. :
2023 AAHA selected endocrinopathies of dogs and cats guidelines. J Am Anim Hosp Assoc 59:113-135, 2023. Pubmed reference: 37167252. DOI: 10.5326/JAAHA-MS-7368.
Chae, Y., Yun, T., Koo, Y., Lee, D., Yang, M.P., Kim, H., Kang, B.T. :
Case report: Central-pituitary hypothyroidism concurrent with hyperadrenocorticism without pituitary macroadenoma in a Miniature Schnauzer dog. Front Vet Sci 10:1257624, 2023. Pubmed reference: 37818388. DOI: 10.3389/fvets.2023.1257624.
Ruijter, B.E.W., Bik, C.A., Schofield, I., Niessen, S.J.M. :
External validation of a United Kingdom primary-care Cushing's prediction tool in a population of referred Dutch dogs. J Vet Intern Med 37:2052-2063, 2023. Pubmed reference: 37665189. DOI: 10.1111/jvim.16848.
Schäfer, I., Rehbein, S., Holtdirk, A., Kottmann, T., Klein, R., Müller, E., Thoren-Tolling, K. :
Diagnostic cut-off values for the urinary corticoid:creatinine ratio for the diagnosis of canine Cushing's syndrome using an automated chemiluminescent assay. Vet Clin Pathol 52:443-451, 2023. Pubmed reference: 37204225. DOI: 10.1111/vcp.13219.
Yokota, S., Kobatake, Y., Maekawa, M., Takashima, S., Nishii, N. :
Trismus due to myotonia associated with hyperadrenocorticism in a dog. J Vet Med Sci 85:876-879, 2023. Pubmed reference: 37357395. DOI: 10.1292/jvms.23-0103.
2022 Imbery, C.A., Dieterle, F., Ottka, C., Weber, C., Schlotterbeck, G., Müller, E., Lohi, H., Giger, U. :
Metabolomic abnormalities in serum from untreated and treated dogs with hyper- and hypoadrenocorticism. Metabolites 12:339, 2022. Pubmed reference: 35448526. DOI: 10.3390/metabo12040339.
Miura, K., Sunahara, H., Sakai, Y., Isshiki, S., Hasegawa, M., Oda, M. :
Effective treatment with mitotane for a canine case of presumed ectopic Cushing's syndrome-related pheochromocytoma. Open Vet J 12:762-767, 2022. Pubmed reference: 36589399. DOI: 10.5455/OVJ.2022.v12.i5.22.
2021 Mora, S.E.V., Romão, F.G., Dos Santos, B., Carvalho, M.D.G., Duarte, R.C.F., De Marco Bernardes, V., Lopes, P.A., Takahira, R.K. :
Thrombin generation assay and hemostatic profile for elucidating hypercoagulability in endogenous canine hyperadrenocorticism. Top Companion Anim Med 45:100581, 2021. Pubmed reference: 34509666. DOI: 10.1016/j.tcam.2021.100581.
2019 Bennaim, M., Shiel, R.E., Mooney, C.T. :
Diagnosis of spontaneous hyperadrenocorticism in dogs. Part 1: Pathophysiology, aetiology, clinical and clinicopathological features. Vet J 252:105342, 2019. Pubmed reference: 31554593. DOI: 10.1016/j.tvjl.2019.105342.
2017 De-Marco, V., Carvalho, L.R., Guzzo, M.F., Oliveira, P.S.L., Gomes, L.G., Mendonca, B.B. :
An activating mutation in the CRHR1 gene is rarely associated with pituitary-dependent hyperadrenocorticism in poodles. Clinics (Sao Paulo) 72:575-581, 2017. Pubmed reference: 29069262. DOI: 10.6061/clinics/2017(09)09.
2016 Del Magno, S., Grinwis, G.C., Voorhout, G., Meij, B.P. :
Dynamic computed tomography of the pituitary gland using a single slice scanner in dogs with pituitary-dependent hypercortisolism. Res Vet Sci 107:42-9, 2016. Pubmed reference: 27473973. DOI: 10.1016/j.rvsc.2016.04.005.
Nagata, N., Kojima, K., Yuki, M. :
Comparison of survival times for dogs with pituitary-dependent hyperadrenocorticism in a primary-care hospital: Treated with trilostane versus untreated. J Vet Intern Med 31:22-28, 2016. Pubmed reference: 27906457. DOI: 10.1111/jvim.14617.
Noh, S., Kim, H.S., Chang, J., Kang, J.H., Chang, D., Yang, M.P. :
Serum cholecystokinin concentrations in dogs with naturally acquired pituitary-dependent hyperadrenocorticism. Am J Vet Res 77:1101-7, 2016. Pubmed reference: 27668581. DOI: 10.2460/ajvr.77.10.1101.
Sato, A., Teshima, T., Ishino, H., Harada, Y., Yogo, T., Kanno, N., Hasegawa, D., Hara, Y. :
A magnetic resonance imaging-based classification system for indication of trans-sphenoidal hypophysectomy in canine pituitary-dependent hypercortisolism. J Small Anim Pract 57:240-6, 2016. Pubmed reference: 27101315. DOI: 10.1111/jsap.12474.
Teshima, T., Matsumoto, H., Okusa, T., Uchiyama, R., Koyama, H. :
Carbenoxolone disodium treatment for canine pituitary-dependent hyperadrenocorticism. PLoS One 11:e0166267, 2016. Pubmed reference: 27824928. DOI: 10.1371/journal.pone.0166267.
2015 Takano, H., Kokubu, A., Sugimoto, K., Sunahara, H., Aoki, T., Fijii, Y. :
Left ventricular structural and functional abnormalities in dogs with hyperadrenocorticism. J Vet Cardiol 17:173-81, 2015. Pubmed reference: 26319177. DOI: 10.1016/j.jvc.2015.07.002.
Tvarijonaviciute, A., Caldin, M., Martinez-Subiela, S., Tecles, F., Pastor, J., Ceron, J.J. :
Serum paraoxonase 1 and butyrylcholinesterase in dogs with hyperadrenocorticism. Vet J 203:262-3, 2015. Pubmed reference: 25555340. DOI: 10.1016/j.tvjl.2014.12.002.
2014 Chen, H.Y., Lien, Y.H., Huang, H.P. :
Assessment of left ventricular function by two-dimensional speckle-tracking echocardiography in small breed dogs with hyperadrenocorticism. Acta Vet Scand 56:88, 2014. Pubmed reference: 25551792. DOI: 10.1186/s13028-014-0088-5.
2013 Bellumori, T.P., Famula, T.R., Bannasch, D.L., Belanger, J.M., Oberbauer, A.M. :
Prevalence of inherited disorders among mixed-breed and purebred dogs: 27,254 cases (1995-2010). J Am Vet Med Assoc 242:1549-55, 2013. Pubmed reference: 23683021. DOI: 10.2460/javma.242.11.1549.
Kol, A., Nelson, R.W., Gosselin, R.C., Borjesson, D.L. :
Characterization of thrombelastography over time in dogs with hyperadrenocorticism. Vet J 197:675-81, 2013. Pubmed reference: 23838206. DOI: 10.1016/j.tvjl.2013.05.047.
2007 Brown, CG., Graves, TK. :
Hyperadrenocorticism: treating dogs. Compend Contin Educ Vet 29:132-4, 136, 138 passim; quiz 144-5, 2007. Pubmed reference: 17726933.
Peterson, ME. :
Diagnosis of hyperadrenocorticism in dogs. Clin Tech Small Anim Pract 22:2-11, 2007. Pubmed reference: 17542191. DOI: 10.1053/j.ctsap.2007.02.007.
2005 Barker, EN., Campbell, S., Tebb, AJ., Neiger, R., Herrtage, ME., Reid, SW., Ramsey, IK. :
A comparison of the survival times of dogs treated with mitotane or trilostane for pituitary-dependent hyperadrenocorticism. J Vet Intern Med 19:810-5, 2005. Pubmed reference: 16355673.
Behrend, EN., Kemppainen, RJ., Boozer, AL., Whitley, EM., Smith, AN., Busch, KA. :
Serum 17-alpha-hydroxyprogesterone and corticosterone concentrations in dogs with nonadrenal neoplasia and dogs with suspected hyperadrenocorticism. J Am Vet Med Assoc 227:1762-7, 2005. Pubmed reference: 16342524.
Benitah, N., Feldman, EC., Kass, PH., Nelson, RW. :
Evaluation of serum 17-hydroxyprogesterone concentration after administration of ACTH in dogs with hyperadrenocorticism. J Am Vet Med Assoc 227:1095-101, 2005. Pubmed reference: 16220669.
Hanson, JM., van 't, HM., Voorhout, G., Teske, E., Kooistra, HS., Meij, BP. :
Efficacy of transsphenoidal hypophysectomy in treatment of dogs with pituitary-dependent hyperadrenocorticism. J Vet Intern Med 19:687-94, 2005. Pubmed reference: 16231713.
Hill, KE., Scott-Moncrieff, JC., Koshko, MA., Glickman, LT., Glickman, NW., Nelson, RW., Blevins, WE., Oliver, JW. :
Secretion of sex hormones in dogs with adrenal dysfunction. J Am Vet Med Assoc 226:556-61, 2005. Pubmed reference: 15742696.
Martínez, N.I., Panciera, D.L., Abbott, J.A., Ward, D.L. :
Evaluation of pressor sensitivity to norepinephrine infusion in dogs with iatrogenic hyperadrenocorticism. Pressor sensitivity in dogs with hyperadrenocorticism. Res Vet Sci 78:25-31, 2005. Pubmed reference: 15500836. DOI: 10.1016/j.rvsc.2004.05.004.
2004 Bryden, SL., Burrows, AK., O'hara, AJ. :
Mycobacterium goodii infection in a dog with concurrent hyperadrenocorticism. Vet Dermatol 15:331-8, 2004. Pubmed reference: 15500486. DOI: 10.1111/j.1365-3164.2004.00383.x.
Wenger, M., Sieber-Ruckstuhl, N.S., Müller, C., Reusch, C.E. :
Effect of trilostane on serum concentrations of aldosterone, cortisol, and potassium in dogs with pituitary-dependent hyperadrenocorticism. Am J Vet Res 65:1245-50, 2004. Pubmed reference: 15478772.
2003 Hess, R.S., Kass, P.H., Van, Winkle, T.J. :
Association between diabetes mellitus, hypothyroidism or hyperadrenocorticism, and atherosclerosis in dogs Journal of Veterinary Internal Medicine 17:489-94, 2003. Pubmed reference: 12892299.
Lee, W.M., Meij, B.P., Bhatti, S.F., Mol, J.A., Rijnberk, A., Kooistra, H.S. :
Pulsatile secretion pattern of growth hormone in dogs with pituitary-dependent hyperadrenocorticism Domestic Animal Endocrinology 24:59-68, 2003. Pubmed reference: 12450625.
2002 Alenza, M.D.P., Guerrero, B., Melian, C., Ynaraja, E., Pena, L. :
Use of aminoglutethimide in the treatment of pituitary-dependent hyperadrenocorticism in the dog Journal of Small Animal Practice 43:104-108, 2002. Pubmed reference: 11924551.
Behrend, E.N., Kemppainen, R.J., Clark, T.P., Salman, M.D., Peterson, M.E. :
Diagnosis of hyperadrenocorticism in dogs: a survey of internists and dermatologists Journal of the American Veterinary Medical Association 220:1643-1649, 2002. Pubmed reference: 12051503.
Bhatti, S.F.M., De Vliegher, S.P., Van Ham, L., Kooistra, H.S. :
Effects of growth hormone-releasing peptides in healthy dogs and in dogs with pituitary-dependent hyperadrenocorticism Molecular & Cellular Endocrinology 197:97-103, 2002.
Bosje, J.T., Rijnberk, A., Mol, J.A., Voorhout, G., Kooistra, H.S. :
Plasma concentrations of ACTH precursors correlate with pituitary size and resistance to dexamethasone in dogs with pituitary-dependent hyperadrenocorticism Domestic Animal Endocrinology 22:201-210, 2002. Pubmed reference: 12044610.
Goy-Thollot, I., Pechereau, D., Keroack, S., Dezempte, J.C., Bonnet, J.M. :
Investigation of the role of aldosterone in hypertension associated with spontaneous pituitary-dependent hyperadrenocorticism in dogs Journal of Small Animal Practice 43:489-492, 2002. Pubmed reference: 12463264.
Laus, J.L., dos, Santos, C., Talieri, I.C., Oria, A.P., Bechara, G.H. :
Combined corneal lipid and calcium degeneration in a dog with hyperadrenocorticism: a case report Veterinary Ophthalmology 5:61-64, 2002. Pubmed reference: 11940251.
Meij, B., Voorhout, G., Rijnberk, A. :
Progress in transsphenoidal hypophysectomy for treatment of pituitary-dependent hyperadrenocorticism in dogs and cats Molecular & Cellular Endocrinology 197:89-96, 2002.
Neiger, R., Ramsey, I., O'Connor, J., Hurley, K.J., Mooney, C.T. :
Trilostane treatment of 78 dogs with pituitary-dependent hyperadrenocorticism Veterinary Record 150:799-804, 2002. Pubmed reference: 12120922.
Ristic, J.M.E., Ramsey, I.K., Heath, F.M., Evans, H.J., Herrtage, M.E. :
The use of 17-hydroxyprogesterone in the diagnosis of canine hyperadrenocorticism Journal of Veterinary Internal Medicine 16:433-439, 2002. Pubmed reference: 12141305.
Schoemaker, N.J., Mol, J.A., Lumeij, J.T., Rijnberk, A. :
I plasma concentrations of adrenocorticotrophic hormone and alpha-melanocyte-stimulating hormone in ferrets (Mustela putorius furo) with hyperadrenocorticism American Journal of Veterinary Research 63:1395-9, 2002. Pubmed reference: 12371766.
van der Vlugt-Meijer, R.H., Voorhout, G., Meij, B.P. :
Imaging of the pituitary gland in dogs with pituitary-dependent hyperadrenocorticism Molecular & Cellular Endocrinology 197:81-87, 2002.
2001 Behrend, E.N., Kemppainen, R.J. :
Diagnosis of canine hyperadrenocorticism Veterinary Clinics of North America - Small Animal Practice 31:985-+, 2001.
Nett, C.S., Reusch, C.E. :
Mitotane (Lysodren((R))) intolerance - alternative treatment options in dogs with pituitary dependent hyperadrenocorticism - a case report Kleintierpraxis 46:725-+, 2001.
2000 Berry, C.R., Hawkins, E.C., Hurley, K.J., Monce, K. :
Frequency of pulmonary mineralization and hypoxemia in 21 dogs with pituitary-dependent hyperadrenocorticism Journal of Veterinary Internal Medicine 14:151-156, 2000. Pubmed reference: 10772486.
Bruyette, D.S. :
Diagnosing hyperadrenocorticism in a hyperactive dog Veterinary Medicine 95:438, 2000.
Bruyette, D.S. :
Treating canine hyperadrenocorticism of unknown etiology Veterinary Medicine 95:828-829, 2000.
Schwarz, T., Stork, C.K., Mellor, D., Sullivan, M. :
Osteopenia and other radiographic signs in canine hyperadrenocorticism Journal of Small Animal Practice 41:491-495, 2000. Pubmed reference: 11105787.
Zerbe, C.A. :
Screening tests to diagnose hyperadrenocorticism in cats and dogs Compendium on Continuing Education for the Practicing Veterinarian 22:17-+, 2000.
Zerbe, C.A. :
Differentiating tests to evaluate hyperadrenocorticism in dogs and cats Compendium on Continuing Education for the Practicing Veterinarian 22:149-+, 2000.
1999 Behrend, E.N., Kemppainen, R.J., Clark, T.P., Salman, M.D., Peterson, M.E. :
Treatment of hyperadrenocorticism in dogs: a survey of internists and dermatologists Journal of the American Veterinary Medical Association 215:938-943, 1999. Pubmed reference: 10511856.
den, Hertog, E., Braakman, J.C.A., Teske, E., Kooistra, H.S., Rijnberk, A. :
Results of non-selective adrenocorticolysis by o,p '-DDD in 129 dogs with pituitary-dependent hyperadrenocorticism Veterinary Record 144:12-17, 1999. Pubmed reference: 10028568.
Forrester, S.D., Troy, G.C., Dalton, M.N., Huffman, J.W., Holtzman, G. :
Retrospective evaluation of urinary tract infection in 42 dogs with hyperadrenocorticism or diabetes mellitus or both Journal of Veterinary Internal Medicine 13:557-560, 1999. Pubmed reference: 10587255.
Gould, S.M., Baines, E.A., Mannion, P.A., Evans, H., Herrtage, M.E. :
Use of endogenous ACTH concentration and adrenal ultrasonography to distinguish the cause of canine hyperadrenocorticism Journal of Small Animal Practice 42:113-121, 1999.
Greco, D.S., Peterson, M.E., Davidson, A.P., Feldman, E.C., Komurek, K. :
Concurrent pituitary and adrenal tumors in dogs with hyperadrenocorticism: 17 cases (1978-1995) Journal of the American Veterinary Medical Association 214:1349-1353, 1999. Pubmed reference: 10319177.
Harris, P. :
Primary hypoadrenocorticism in a dog receiving glucocorticoid supplementation Canadian Veterinary Journal - Revue Veterinaire Canadienne 40:129-131, 1999.
Horauf, A., Reusch, C. :
Effect of mitotane therapy on adrenal gland size in dogs with pituitary dependent hyperadrenocorticism - an ultrasonographic study [German] Schweizer Archiv fur Tierheilkunde 141:239-245, 1999. Pubmed reference: 10354742.
Huang, H.P., Yang, H.L., Liang, S.L., Lien, Y.H., Chen, K.Y. :
Latrogenic hyperadrenocorticism in 28 Dogs Journal of the American Animal Hospital Association 35:200-207, 1999. Pubmed reference: 10333257.
Kerl, M.E., Peterson, M.E., Wallace, M.S., Melian, C., Kemppainen, R.J. :
Evaluation of a low-dose synthetic adrenocorticotropic hormone stimulation test in clinically normal dogs and dogs with naturally developing hyperadrenocorticism Journal of the American Veterinary Medical Association 214:1497-1501, 1999. Pubmed reference: 10340075.
Melian, C., Stefanacci, J., Peterson, M.E., Kintzer, P.P. :
Radiographic findings in dogs with naturally-occurring primary hypoadrenocorticism Journal of the American Animal Hospital Association 35:208-212, 1999. Pubmed reference: 10333258.
Norman, E.J., Thompson, H., Mooney, C.T. :
Dynamic adrenal function testing in eight dogs with hyperadrenocorticism associated with adrenocortical neoplasia Veterinary Record 144:551-554, 1999. Pubmed reference: 10371012.
Peterson, M.E. :
Medical treatment of pituitary-dependent hyperadrenocorticism in dogs: Should L-deprenyl (Anipryl) ever be used? Journal of Veterinary Internal Medicine 13:289-290, 1999. Pubmed reference: 10449217.
Reusch, C.E., Steffen, T., Hoerauf, A. :
The efficacy of L-Deprenyl in dogs with pituitary-dependent hyperadrenocorticism Journal of Veterinary Internal Medicine 13:291-301, 1999. Pubmed reference: 10449218.
Zerbe, C.A. :
The hypothalamic-pituitary-adrenal axis and pathophysiology of hyperadrenocorticism Compendium on Continuing Education for the Practicing Veterinarian 21:1134-+, 1999.
1998 Anon. :
Evaluation of urine protein content in dogs with pituitary-dependent hyperadrenocorticism (vol 212, pg 369, 1998) Journal of the American Veterinary Medical Association 213:644, 1998.
Bennett, P.F., Norman, E.J. :
Mitotane (o,p'-ddd) resistance in a dog with pituitary-dependent hyperadrenocorticism and phaeochromocytoma Australian Veterinary Journal 76:101-103, 1998. Pubmed reference: 9578778.
Goossens, M.M.C., Feldman, E.C., Theon, A.P., Koblik, P.D. :
Efficacy of cobalt 60 radiotherapy in dogs with pituitary-dependent hyperadrenocorticism Journal of the American Veterinary Medical Association 212:374 ff., 1998.
Hess, R.S., Ward, C.R. :
Diabetes mellitus, hyperadrenocorticism, and hypothyroidism in a dog Journal of the American Animal Hospital Association 34:204-207, 1998. Pubmed reference: 9590447.
Hess, R.S., Ward, C.R. :
Concurrent canine hyperadrenocorticism and diabetes mellitus - diagnosis and treatment Compendium on Continuing Education for the Practicing Veterinarian 20:701 ff., 1998.
Hurley, K.J., Vaden, S.L. :
Evaluation of urine protein content in dogs with pituitary-dependent hyperadrenocorticism Journal of the American Veterinary Medical Association 212:369 ff., 1998.
Meij, B.P., Voorhout, G., Vandeningh, T.S.G.A.M., Hazewinkel, H.A.W., Teske, E., Rijnberk, A. :
Results of transsphenoidal hypophysectomy in 52 dogs with pituitary-dependent hyperadrenocorticism Veterinary Surgery 27:246-261, 1998. Pubmed reference: 9605236.
Randolph, J.F., Toomey, J., Center, S.A., Scarlett, J.M., Reimers, T., Graham, P., Nachreiner, R.F. :
Use of the urine cortisol-to-creatinine ratio for monitoring dogs with pituitary-dependent hyperadrenocorticism during induction treatment with mitotane (o,p'-ddd) American Journal of Veterinary Research 59:258-261, 1998. Pubmed reference: 9522940.
Rubin, S.I., Toolan, L., Halperin, M.L. :
Trimethoprim-induced exacerbation of hyperkalemia in a dog with hypoadrenocorticism Journal of Veterinary Internal Medicine 12:186-188, 1998. Pubmed reference: 9595382.
Swinney, G.B., Foster, S.F., Church, D.B., Malik, R. :
Myotonia associated with hyperadrenocorticism in two dogs Australian Veterinary Journal 76:722-724, 1998. Pubmed reference: 9862060.
Thuroczy, J., Balogh, L., Huszenicza, G., Janoki, G.A., Kulcsar, M. :
Diagnosis of hyperadrenocorticism in dogs as compared to human diagnostic methods - a review Acta Veterinaria Hungarica 46:157-173, 1998. Pubmed reference: 9704520.
1997 Angles, J.M., Feldman, E.C., Nelson, R.W., Feldman, M.S. :
Use of urine cortisol-creatinine ratio versus adrenocorticotropic hormone stimulation testing for monitoring mitotane treatment of pituitary-dependent hyperadrenocorticism in dogs Journal of the American Veterinary Medical Association 211:1002 ff., 1997.
Bruyette, D.S., Ruehl, W.W., Entriken, T., Griffin, D., Darling, L. :
Management of canine pituitary-dependent hyperadrenocorticism with 1-deprenyl (anipryl) Veterinary Clinics of North America - Small Animal Practice 27:273 ff., 1997.
Bruyette, D.S., Ruehl, W.W., Entriken, T.L., Darling, L.A., Griffin, D.W. :
Treating canine pituitary-dependent hyperadrenocorticism with l-deprenyl Veterinary Medicine 92:710 ff., 1997.
Denhertog, E., Braakman, J.C.A., Teske, E., Kooistra, H.S., Rijnberk, A. :
Treatment of pituitary-dependent hyperadrenocorticism in the dog by non-selective adrenocorticolysis with o,p'-ddd Veterinary Quarterly 19:S 17, 1997.
Galac, S., Kooistra, H.S., Teske, E., Rijnberk, A. :
Urinary corticoid/creatinine ratios in the differentiation between pituitary-dependent hyperadrenocorticism and hyperadrenocorticism due to adrenocortical tumour in the dog Veterinary Quarterly 19:17-20, 1997. Pubmed reference: 9225424.
Guptill, L., Scottmoncrieff, J.C., Widmer, W.R. :
Diagnosis of canine hyperadrenocorticism Veterinary Clinics of North America - Small Animal Practice 27:215 ff., 1997.
Guptill, L., Scottmoncrieff, J.C., Bottoms, G., Glickman, L., Johnson, M., Glickman, N., Nelson, R., Bertoy, E. :
Use of the urine cortisol/creatinine ratio to monitor treatment response in dogs with pituitary-dependent hyperadrenocorticism Journal of the American Veterinary Medical Association 210:1158 ff., 1997.
Jensen, A.L., Iversen, L., Koch, J., Hoier, R., Petersen, T.K. :
Evaluation of the urinary cortisol - creatinine ratio in the diagnosis of hyperadrenocorticism in dogs Journal of Small Animal Practice 38:99-102, 1997. Pubmed reference: 9097240.
Kooistra, H.S., Voorhout, G., Mol, J.A., Rijnberk, A. :
Correlation between impairment of glucocorticoid feedback and the size of the pituitary gland in dogs with pituitary-dependent hyperadrenocorticism Journal of Endocrinology 152:387-394, 1997. Pubmed reference: 9071959.
Mackay, B.M. :
Hyperadrenocorticism in the dog [Review] Australian Veterinary Practitioner 27:147 ff., 1997.
Meij, B.P., Mol, J.A., Bevers, M.M., Rijnberk, A. :
Alterations in anterior pituitary function of dogs with pituitary-dependent hyperadrenocorticism Journal of Endocrinology 154:505-512, 1997. Pubmed reference: 9379128.
Meij, B.P., Mol, J.A., Bevers, M.M., Rijnberk, A. :
Residual pituitary function after transsphenoidal hypophysectomy in dogs with pituitary-dependent hyperadrenocorticism Journal of Endocrinology 155:531-539, 1997. Pubmed reference: 9487998.
Miyamoto, T., Horie, T., Ogawa, Y., Baba, E., Kuwamura, M. :
Hyperadrenocorticism with severe calcinosis cutis in a dog Canine Practice 22:24 ff., 1997.
Nichols, R. :
Complications and concurrent disease associated with canine hyperadrenocorticism Veterinary Clinics of North America - Small Animal Practice 27:309 ff., 1997.
Peterson, M.E., Kintzer, P.P. :
Medical treatment of pituitary-dependent hyperadrenocorticism - mitotane Veterinary Clinics of North America - Small Animal Practice 27:255 ff., 1997.
Vanwijk, P.A., Rijnberk, A., Croughs, R.J.M., Meij, B.P., Vanleeuwen, I.S., Sprang, E.P.M., Mol, J.A. :
Molecular screening for somatic mutations in corticotropic adenomas of dogs with pituitary-dependent hyperadrenocorticism Journal of Endocrinological Investigation 20:1-7, 1997. Pubmed reference: 9075064.
Vanwijk, P.A.M., Croughs, R.J.M., Rijnberk, A., Mol, J.A. :
In vivo and in vitro characteristics of corticotropic adenomas of dogs with pituitary-dependent hyperadrenocorticism Veterinary Quarterly 19:S 10-S 11, 1997.
1996 Bertoy, E.H., Feldman, E.C., Nelson, R.W., Dublin, A.B., Reid, M.H., Feldman, M.S. :
One-year follow-up evaluation of magnetic resonance imaging of the brain in dogs with pituitary-dependent hyperadrenocorticism Journal of the American Veterinary Medical Association 208:1268 ff., 1996.
Galac, S., Kooistra, H.S. :
Urinary corticoid/creatinine ratio in dogs with hyperadrenocorticism Veterinary Quarterly 18:S 35, 1996.
Grooters, A.M., Biller, D.S., Theisen, S.K., Miyabayashi, T. :
Ultrasonographic characteristics of the adrenal glands in dogs with pituitary-dependent hyperadrenocorticism - comparison with normal dogs Journal of Veterinary Internal Medicine 10:110-115, 1996. Pubmed reference: 8743208.
Montgomery, T.M., Nelson, R.W., Feldman, E.C., Robertson, K., Polonsky, K.S. :
Basal and glucagon-stimulated plasma c-peptide concentrations in healthy dogs, dogs with diabetes mellitus, and dogs with hyperadrenocorticism Journal of Veterinary Internal Medicine 10:116-122, 1996. Pubmed reference: 8743209.
Nelson, R.W. :
Diagnosis and medical treatment of pituitary-dependent hyperadrenocorticism Veterinary Quarterly 18:S 26-S 27, 1996.
Ortega, T.M., Feldman, E.C., Nelson, R.W., Willits, N., Cowgill, L.D. :
Systemic arterial blood pressure and urine protein/creatinine ratio in dogs with hyperadrenocorticism Journal of the American Veterinary Medical Association 209:1724-1729, 1996. Pubmed reference: 8921029.
Soffner, C., Reusch, C. :
Assessment of urinary cortisol/creatinine ratio in the diagnosis of hyperadrenocorticism in dogs [German] Kleintierpraxis 41:85 ff., 1996.
1995 Bertoy, E.H., Feldman, E.C., Nelson, R.W., Duesberg, C.A., Kass, P.H., Reid, M.H., Dublin, A.B. :
Magnetic resonance Imaging of the brain in dogs with recently diagnosed but untreated pituitary-dependent hyperadrenocorticism Journal of the American Veterinary Medical Association 206:651-656, 1995. Pubmed reference: 7744686.
Horauf, A., Reusch, C. :
Visualisation of the suprarenal glands by means of ultrasound: Examinations in healthy dogs, in dogs with non-endocrine diseases as well as in dogs with hyperadrenocorticism Kleintierpraxis 40:351, 1995.
Kaplan, A.J., Peterson, M.E. :
Effects of desoxycorticosterone pivalate administration on blood pressure in dogs with primary hypoadrenocorticism Journal of the American Veterinary Medical Association 206:327-331, 1995. Pubmed reference: 7751240.
Thiessen, A.E., Cowell, R.L., Clinkenbeard, K.D., Meinkoth, J.H., Sherrell, S. :
Hypoadrenocorticism in a puppy Canine Practice 20:18-22, 1995.
Vondehn, B.J., Nelson, R.W., Feldman, E.C., Griffey, S.M. :
Pheochromocytoma and hyperadrenocorticism in dogs: Six cases (1982-1992) Journal of the American Veterinary Medical Association 207:322-324, 1995. Pubmed reference: 7628933.
Whitley, N.T. :
Megaoesophagus and glucocorticoid-deficient hypoadrenocorticism in a dog Journal of Small Animal Practice 36:132-135, 1995. Pubmed reference: 7783439.
Widmer, W.R., Guptill, L. :
Clinical update - Imaging techniques for facilitating diagnosis of hyperadrenocorticism in dogs and cats Journal of the American Veterinary Medical Association 206:1857-1864, 1995. Pubmed reference: 7790297.
1994 Mack, R.E., Wilson, S.M., Feldman, E.C. :
Diagnosis of Hyperadrenocorticism in Dogs Compendium on Continuing Education for the Practicing Veterinarian 16:311, 1994.
Mack, R.E. :
Screening Tests Used in the Diagnosis of Canine Hyperadenocorticism Seminars in Veterinary Medicine and Surgery - Small Animal 9:118-122, 1994. Pubmed reference: 7938929.
Nichols, R. :
Concurrent Illness and Complications Associated with Canine Hyperadrenocorticism Seminars in Veterinary Medicine and Surgery - Small Animal 9:132-136, 1994. Pubmed reference: 7938932.
Peterson, M.E., Kintzer, P.P. :
Medical Treatment of Pituitary-Dependent Hyperadrenocorticism in Dogs Seminars in Veterinary Medicine and Surgery - Small Animal 9:127-131, 1994. Pubmed reference: 7938931.
Stewart, L.J. :
The Integumentary Changes of Hyperadrenocorticism Seminars in Veterinary Medicine and Surgery - Small Animal 9:123-126, 1994. Pubmed reference: 7938930.
1993 Barrie, J., Watson, T.D.G., Stear, M.J., Nash, A.S. :
Plasma Cholesterol and Lipoprotein Concentrations in the Dog - The Effects of Age, Breed, Gender and Endocrine Disease Journal of Small Animal Practice 34:507-512, 1993.
Cayzer, J., Jones, B.R. :
Canine Hyperadrenocorticism New Zealand Veterinary Journal 41:53-68, 1993.
Janssens, L.A.A., Janssens, D.L. :
Successful Long Term Ketoconazole Treatment of Hyperadrenocorticism in a Dog Vlaams Diergeneeskundig Tijdschrift 62:186-188, 1993.
Kemppainen, R.J., Peterson, M.E. :
Circulating Concentration of Dexamethasone in Healthy Dogs, Dogs with Hyperadrenocorticism, and Dogs with Nonadrenal Illness During Dexamethasone Suppression Testing American Journal of Veterinary Research 54:1765-1769, 1993. Pubmed reference: 8250405.
Smiley, L.E., Peterson, M.E. :
Evaluation of a Urine Cortisol - Creatinine Ratio as a Screening Test for Hyperadrenocorticism in Dogs Journal of Veterinary Internal Medicine 7:163-168, 1993. Pubmed reference: 8331610.
1992 Scholten-Sloof, BE., Knol, BW., Rijnberk, A., Mol, JA., Middleton, DJ., Ubbink, GJ. :
Pituitary-dependent hyperadrenocorticism in a family of Dandie Dinmont terriers. J Endocrinol 135:535-42, 1992. Pubmed reference: 1487706.
van Sluijs, F.J., Sjollema, B.E. :
Adrenalectomy in 36 dogs and 2 cats with hyperadrenocorticism. Tijdschr Diergeneeskd 117 Suppl 1:29S, 1992. Pubmed reference: 1585317.
1991 Wolfsheimer, K.J., Peterson, M.E. :
Erythrocyte Insulin Receptors in Dogs with Spontaneous Hyperadrenocorticism American Journal of Veterinary Research 52:917-921, 1991. Pubmed reference: 1883096.
1990 Blaxter, A.C., Gruffydd-Jones, T.J. :
Concurrent Diabetes Mellitus and Hyperadrenocorticism in the Dog - Diagnosis and Management of 8 Cases Journal of Small Animal Practice 31:117-122, 1990.
Mauldin, G.N., Burk, R.L. :
The use of diagnostic computerized tomography and radiation therapy in canine and feline hyperadrenocorticism. Probl Vet Med 2:557-64, 1990. Pubmed reference: 2134074.

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  • Created by Frank Nicholas on 06 Sep 2005
  • Changed by Imke Tammen2 on 03 Feb 2023