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OMIA 000494-9796 : Hyperadrenocorticism, generic in Equus caballus

In other species: domestic cat , dog , domestic ferret

Possibly relevant human trait(s) and/or gene(s)s (MIM numbers): 169170 (trait) , 201710 (trait)

Mendelian trait/disorder: unknown

Considered a defect: yes

Cross-species summary: Hyperadrenocorticism (or Cushing syndrome) refers to genetic and iatrogenic hypersecretion of adrenocorticotropic hormone (ACTH) (e.g. caused by tumours of either the pituitary or adrenal glands; or long-term administration of exogenous glucocorticoids). Entries for Cushing disease (pituitary-dependent hyperadrenocorticism) are included here and for some species also under the OMIA phene Cushing disease (OMIA000247)

Species-specific name: Also know as Pituitary Pars Intermedia Dysfunction or Cushing disease

Species-specific symbol: PPID

References


Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.
2013 Smiet, E. :
[Equine Cushing's disease; an update]. Tijdschr Diergeneeskd 138:162-5, 2013. Pubmed reference: 23513997.
2004 Johnson, PJ., Messer, NT., Ganjam, VK. :
Cushing's syndromes, insulin resistance and endocrinopathic laminitis. Equine Vet J 36:194-8, 2004. Pubmed reference: 15147141.
Keen, JA., McLaren, M., Chandler, KJ., McGorum, BC. :
Biochemical indices of vascular function, glucose metabolism and oxidative stress in horses with equine Cushing's disease. Equine Vet J 36:226-9, 2004. Pubmed reference: 15147123.
Sgorbini, M., Panzani, D., Maccheroni, M., Corazza, M. :
Equine cushing-like syndrome: diagnosis and therapy in two cases. Vet Res Commun 28 Suppl 1:377-80, 2004. Pubmed reference: 15373001.
2002 Donaldson, M.T., LaMonte, B.H., Morresey, P., Smith, G., Beech, J. :
Treatment with pergolide or cyproheptadine of pituitary pars intermedia dysfunction (equine Cushing's disease) Journal of Veterinary Internal Medicine 16:742-746, 2002. Pubmed reference: 12465775.
Johnson, P.J. :
The equine metabolic syndrome peripheral Cushing's syndrome Veterinary Clinics of North America - Equine Practice 18:271-+, 2002.
McCue, P.M. :
Equine Cushing's disease Veterinary Clinics of North America - Equine Practice 18:533-43, viii, 2002.
Schott, H.C. :
Pituitary pars intermedia dysfunction: equine Cushing's disease Veterinary Clinics of North America - Equine Practice 18:237-+, 2002.
2001 Reeves, H.J., Lees, R., McGowan, C.M. :
Measurement of basal serum insulin concentration in the diagnosis of Cushing's disease in ponies Veterinary Record 149:449-452, 2001. Pubmed reference: 11688747.
van der Kolk, J.H., Ijzer, J., Overgaauw, P.A.M., van der Linde-Sipman, J.S. :
Pituitary-independent Cushing's syndrome in a horse Equine Veterinary Journal 33:110-112, 2001. Pubmed reference: 11191603.
2000 Dybdal, N. :
Equine Cushing's disease research (Reprinted from UCD Horse Report) Journal of Equine Veterinary Science 20:87-+, 2000.
Harman, J.C. :
Natural medicine for Cushing's syndrome Journal of Equine Veterinary Science 20:84-+, 2000.
van der Kolk, J.H., Wensing, T. :
Urinary concentration of corticoids in ponies with hyperlipoproteinaemia or hyperadrenocorticism Veterinary Quarterly 22:55-57, 2000. Pubmed reference: 10682389.
Wlaschitz, S., Frohlich, W., Riedelberger, K. :
The Equine Cushing's syndrome in a female horse [German] Wiener Tierarztliche Monatsschrift 87:130-137, 2000.
1999 Douglas, R. :
Circadian cortisol rhythmicity and equine Cushing's-like disease Journal of Equine Veterinary Science 19:684-+, 1999.
Levy, M., Sojka, J.E., Dybdal, N.O. :
Diagnosis and treatment of equine Cushing's disease Compendium on Continuing Education for the Practicing Veterinarian 21:766-769, 1999.
1998 Froin, H.R., Assmann, G., Hoppen, H.O. :
[Equine Cushings-syndrome] [German] Praktische Tierarzt 79:16-21, 1998.
1997 Daft, B.M., Barr, B.C., Collins, N., Sverlow, K. :
Neospora encephalomyelitis and polyradiculoneuritis in an aged mare with cushings-disease Equine Veterinary Journal 29:240-243, 1997. Pubmed reference: 9234020.
Mazan, M.R. :
Medical management of a full-thickness tear of the retroperitoneal portion of the rectum in a horse with hyperadrenocorticism Journal of the American Veterinary Medical Association 210:665 ff., 1997.
Okada, T., Yuguchi, K., Kiso, Y., Morikawa, Y., Nambo, Y., Oikawa, M., Sasaki, F. :
A case of a pony with cushings disease Journal of Veterinary Medical Science 59:707-710, 1997. Pubmed reference: 9300369.
1996 Carrasco, L., Mendez, A., Jensen, H.E. :
Chronic bronchopulmonary aspergillosis in a horse with Cushings-syndrome Mycoses 39:443-447, 1996. Pubmed reference: 9145001.
Couetil, L., Paradis, M.R., Knoll, J. :
Plasma adrenocorticotropin concentration in healthy horses and in horses with clinical signs of hyperadrenocorticism Journal of Veterinary Internal Medicine 10:1-6, 1996. Pubmed reference: 8965262.
Couetil, L.L. :
New developments in equine Cushing's disease Equine Practice 18:28-32, 1996.
Munoz, M.C., Doreste, F., Ferrer, O., Gonzalez, J., Montoya, J.A. :
Pergolide treatment for cushings syndrome in a horse Veterinary Record 139:41-43, 1996. Pubmed reference: 8839490.
1995 Thompson, J.C., Ellison, R., Gillett, R., Badcoe, L. :
Problems in the diagnosis of pituitary adenoma (Cushing's syndrome) in horses New Zealand Veterinary Journal 43:79-82, 1995.
Vanderkolk, J.H., Wensing, T., Kalsbeek, H.C., Breukink, H.J. :
Lipid metabolism in horses with hyperadrenocorticism Journal of the American Veterinary Medical Association 206:1010-1012, 1995. Pubmed reference: 7768707.
1993 Love, S. :
Equine Cushing's Disease British Veterinary Journal 149:139-153, 1993. Pubmed reference: 8485640. DOI: 10.1016/S0007-1935(05)80084-3.

Edit History


  • Created by Frank Nicholas on 06 Sep 2005
  • Changed by Carrie Finno on 11 Dec 2013