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OMIA:000494-9669 : Cushing syndrome, generic in Mustela putorius furo (domestic ferret)

In other species: dog , domestic cat , domestic horse , rabbit , golden hamster , domestic guinea pig

Categories: Endocrine / exocrine gland phene (incl mammary gland)

Links to possible relevant human trait(s) and/or gene(s) in OMIM: 169170 (trait) , 201710 (trait)

Single-gene trait/disorder: unknown

Disease-related: yes

Cross-species summary: Cushing syndrome (or hyperadrenocorticism) refers to a group of clinical syndromes that are caused by a chronic excess of glucocorticoid activity, which can be due to a range of endogenous (e.g., genetic or neoplasms) or exogenous (iatrogenic) steroid hormones. (Modified from ALIVE recommendations (PMID:40872711). Entries for Cushing syndrome - ACTH-Dependent—Pituitary-Dependent Hypercortisolism Cushing syndrome may be included here and for some species also under OMIA:000247. Renamed from 'Hyperadrenocorticism, generic' to 'Cushing syndrome, generic' [10/09/2025].

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Cite this entry

Nicholas, F. W., Tammen, I., & Sydney Informatics Hub. (2005). OMIA:000494-9669: Online Mendelian Inheritance in Animals (OMIA) [dataset]. https://omia.org/. https://doi.org/10.25910/2AMR-PV70

References

Note: the references are listed in reverse chronological order (from the most recent year to the earliest year), and alphabetically by first author within a year.

2025 Jekl, V. :
Adrenal disease in small mammals. Vet Clin North Am Exot Anim Pract 28:S1094-9194(24)00039-2:87-106, 2025. Pubmed reference: 39414475. DOI: 10.1016/j.cvex.2024.07.003.
Niessen, S.J.M., Behrend, E.N., Fracassi, F., Church, D.B., Foster, S.F., Galac, S., Melian, C., Pöppl, Á.G., Ramsey, I.K., Sieber-Ruckstuhl, N.S. :
Agreeing Language in Veterinary Endocrinology (ALIVE): Cushing's syndrome and hypoadrenocorticism-A modified Delphi-method-based system to create consensus definitions. Vet Sci 12:761, 2025. Pubmed reference: 40872711. DOI: 10.3390/vetsci12080761.
2013 de Jong, M.K., Schoemaker, N.J., Mol, J.A. :
Expression of sfrp1 and activation of the Wnt pathway in the adrenal glands of healthy ferrets and neutered ferrets with hyperadrenocorticism. Vet J 196:176-80, 2013. Pubmed reference: 23117029. DOI: 10.1016/j.tvjl.2012.09.022.
2002 Schoemaker, N.J., Teerds, K.J., Mol, J.A., Lumeij, J.T., Thijssen, J.H.H., Rijnberk, A. :
The role of luteinizing hormone in the pathogenesis of hyperadrenocorticism in neutered ferrets Molecular & Cellular Endocrinology 197:117-125, 2002.
Schoemaker, N.J., Teerds, K.J., Mol, J.A., Lumeij, J.T., Thijssen, J.H., Rijnberk, A. :
The role of luteinizing hormone in the pathogenesis of hyperadrenocorticism in neutered ferrets Molecular & Cellular Endocrinology 197:117-25, 2002.
2000 Shoemaker, N.J., Schuurmans, M., Moorman, H., Lumeij, J.T.T. :
Correlation between age at neutering and age at onset of hyperadrenocorticism in ferrets Journal of the American Veterinary Medical Association 216:195-197, 2000. Pubmed reference: 10649752.
1997 Lumeij, J.T. :
Hyperadrenocorticism in the ferret [Dutch] Tijdschrift voor Diergeneeskunde 122:146-147, 1997. Pubmed reference: 9173596.
Weiss, C.A., Scott, M.V. :
Clinical aspects and surgical treatment of hyperadrenocorticism in the domestic ferret - 94 cases (1994-1996) Journal of the American Animal Hospital Association 33:487-493, 1997. Pubmed reference: 9358415.
1996 Rosenthal, K.L., Peterson, M.E. :
Evaluation of plasma androgen and estrogen concentrations in ferrets with hyperadrenocorticism Journal of the American Veterinary Medical Association 209:1097 ff., 1996.

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  • Created by Frank Nicholas on 06 Sep 2005