OMIA:000496 : Hyperbilirubinaemia I |
Categories: Homeostasis / metabolism phene
Possible human homologues (MIM numbers): 143500 (trait) , 191740 (gene) , 218800 (trait)
Cross-species summary: Bilirubin is an orange bile pigment produced by the breakdown of haem and reduction of biliverdinin. An excess of bilirubin in the blood, resulting from a defect in uptake of organic anions by the liver, is called hyperbilirubinaemia I or Gilbert's syndrome. Another anion unable to be taken up by affected livers is phylloerythrin, a metabolite of chlorophyll. The resultant high blood levels of phylloerythrin result in photosensitive dermatitis. [Researched by Philippa Beard]
Species in which this phene is found:
horse (Equus caballus)
sheep (Ovis aries)
Bolivian squirrel monkey (Saimiri boliviensis)
Edit History
- Created by Frank Nicholas on 03 May 2005
- Changed by Imke Tammen2 on 14 Oct 2022